DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15696 and Msx1

DIOPT Version :9

Sequence 1:	NP_650921.1	Gene:	CG15696 / 42469	FlyBaseID:	FBgn0038833	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_034965.2	Gene:	Msx1 / 17701	MGIID:	97168	Length:	303	Species:	Mus musculus

Alignment Length:	175	Identity:	59/175 - (33%)
Similarity:	81/175 - (46%)	Gaps:	33/175 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSIEYILNRAGDRYVGTNASLGV----LQRLRASLPFHPYAHPASYVSKESGGSP---------- 54
            ||:|.::  |..|..|...|:.|    .|....|:. |....|.|..:.::..||
Mouse    61 FSVEALM--ADHRKPGAKESVLVASEGAQAAGGSVQ-HLGTRPGSLGAPDAPSSPRPLGHFSVGG 122

  Fly    55 ----PASA-AEAQIPV----YDWLQYTRYHPPKLPRALRQNAPA----KRTPGRLPRIPFTPQQL 106
                |..| .:|:.|.    ..|:|..|:.||.   |.|.:.||    |....|.||.|||..||
Mouse   123 LLKLPEDALVKAESPEKLDRTPWMQSPRFSPPP---ARRLSPPACTLRKHKTNRKPRTPFTTAQL 184

  Fly   107 QALENAYKESNYLSAEDANKLADSLELTNTRVKIWFQNRRARERR 151
            .|||..:::..|||..:..:.:.||.||.|:||||||||||:.:|
Mouse   185 LALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeobox	97..144	CDD:278475	23/46 (50%)
Msx1	NP_034965.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..53
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..112		4/22 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..163		8/30 (27%)
		Homeobox	175..228	CDD:278475	28/52 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000776
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770