DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15696 and DLX2

DIOPT Version :9

Sequence 1:	NP_650921.1	Gene:	CG15696 / 42469	FlyBaseID:	FBgn0038833	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_004396.1	Gene:	DLX2 / 1746	HGNCID:	2915	Length:	328	Species:	Homo sapiens

Alignment Length:	151	Identity:	48/151 - (31%)
Similarity:	72/151 - (47%)	Gaps:	21/151 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PYAHPASYVSKESG-GSPPASAAEAQIPVYD---WLQYTRYHPPKLPRALRQNAPAKR------- 91
            ||||..||..:.|| .:.|.||..:    ||   ...||.|.|.....:...|.|.|.
Human    83 PYAHMGSYQYQASGLNNVPYSAKSS----YDLGYTAAYTSYAPYGTSSSPANNEPEKEDLEPEIR 143

  Fly    92 ------TPGRLPRIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRVKIWFQNRRARER 150
                  ...|.||..::..||.||:..::::.||:..:..:||.||.||.|:|||||||||::.:
Human   144 IVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFK 208

  Fly   151 REKREKDESCDSTFSSNASSP 171
            :..:..:...:....::||.|
Human   209 KMWKSGEIPSEQHPGASASPP 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeobox	97..144	CDD:278475	20/46 (43%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..81
		DLL_N	51..132	CDD:289198	17/52 (33%)
		Homeobox	155..208	CDD:278475	24/52 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..270		3/19 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810