Protein Alignment CG15696 and Hhex

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 181
• Identity: 51/181 - (28%)
• Similarity: 74/181 - (40%)
• Gaps: 56/181 - (30%)

  Fly    35 PFHP--YAHPASYVSKESGGSPPASAAEAQIPVYDWLQ----YT----RYHP--------PKLPR 81
            |.||  ..|||:.::...|.|....      |:|.:.:    ||    |:.|        |.|.|
Mouse    75 PVHPAFSHHPAAALAAAYGPSGFGG------PLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQR 133

  Fly    82 ALRQNAPAKRTPGRLPRIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRVKIWFQNRR 146
            .|.     ||..|   ::.|:..|...||..::...|||..:..:||..|:|:..:||.||||||
Mouse   134 PLH-----KRKGG---QVRFSNDQTVELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRR 190

  Fly   147 ARERREKREK------------DESCD------------STFSSNASSPEP 173
            |:.||.|:|.            |.||:            ::...:..||.|
Mouse   191 AKWRRLKQENPQSNKKDALDSLDTSCEQGQDLPSEQNKGASLDRSQCSPSP 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	15/48 (31%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		18/73 (25%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		32/107 (30%)
		Homeodomain	143..195	CDD:459649	20/51 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		9/47 (19%)