Protein Alignment CG15696 and NKX2-5

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_004378.1
• Gene: NKX2-5 / 1482
• HGNCID: 2488
• Length: 324
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 55/175 - (31%)
• Similarity: 79/175 - (45%)
• Gaps: 33/175 - (18%)

  Fly    15 DRYVGTNASLGVLQRLRASL-------------PFHPYAHPASYVSKESGGSPPASAAE---AQI 63
            :.|.|..|:...|..|||.|             |..|..:|.:|...:....|.|...|   .|.
Human    54 EAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQK 118

  Fly    64 PVYDWLQYTRYHPPKLPRALRQNAPAKRTPGRLPRIPFTPQQLQALENAYKESNYLSAEDANKLA 128
            .|.  |:.|.....:.|||.|:         |.||:.|:..|:..||..:|:..||||.:.::||
Human   119 AVE--LEKTEADNAERPRARRR---------RKPRVLFSQAQVYELERRFKQQRYLSAPERDQLA 172

  Fly   129 DSLELTNTRVKIWFQNRRARERREKREKDESCDSTFSSNASSPEP 173
            ..|:||:|:|||||||||.:.:|:::      |.|.......|.|
Human   173 SVLKLTSTQVKIWFQNRRYKCKRQRQ------DQTLELVGLPPPP 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	23/48 (48%)
NKX2-5	NP_004378.1	Homeodomain	145..195	CDD:459649	24/49 (49%)