Protein Alignment CG15696 and CDX1

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001795.2
• Gene: CDX1 / 1044
• HGNCID: 1805
• Length: 265
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 59/236 - (25%)
• Similarity: 84/236 - (35%)
• Gaps: 77/236 - (32%)

  Fly     6 IEYILNRAGDRYVG--TNASLGVLQRLRASLPFHPYAHP-----ASYVSKESGGSPP-ASAAEAQ 62
            :.|:|::....|.|  ..||||:..:.... |..|.|.|     :||...|...:|| |..|...
Human     3 VGYVLDKDSPVYPGPARPASLGLGPQAYGP-PAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFP 66

  Fly    63 IPVYDWLQYTRYHP-PKLPRALRQN---------APAKRTPGRLP-------------------- 97
            .|..||.  ..|.| |..|.|...:         :|....||..|
Human    67 APKDDWA--AAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQR 129

  Fly    98 ----------------------------RIPFTPQQLQALENAYKESNYLSAEDANKLADSLELT 134
                                        |:.:|..|...||..:..|.|::....::||.:|.||
Human   130 PTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLT 194

  Fly   135 NTRVKIWFQNRRARERREKREKDESCDSTFSSNASSPEPEM 175
            ..:||||||||||:||:..::|.:        ....|:|.|
Human   195 ERQVKIWFQNRRAKERKVNKKKQQ--------QQQPPQPPM 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	18/96 (19%)
CDX1	NP_001795.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	9..153		29/146 (20%)
		Caudal_act	13..142	CDD:461413	29/131 (22%)
		Homeodomain	156..211	CDD:459649	23/54 (43%)
		Interaction with DNA. /evidence=ECO:0000305|PubMed:28473536	157..178		6/20 (30%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000305|PubMed:28473536	196..207		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..265		7/29 (24%)