DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15695 and CG7120

DIOPT Version :9

Sequence 1:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster
Sequence 2:	NP_001246667.1	Gene:	CG7120 / 38954	FlyBaseID:	FBgn0035888	Length:	701	Species:	Drosophila melanogaster

Alignment Length:	770	Identity:	250/770 - (32%)
Similarity:	370/770 - (48%)	Gaps:	141/770 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SEEQEPNE-------------SKKPLNWIVKILFVVLALFTLVIYTLSGANNPLKNNADPFSPWK 62
            ||.:||..             ..:||....|.:..:|..||...:
  Fly    13 SESEEPEVHMTRRAGGVLHAIQHRPLPVSRKSVLGLLVSFTFCYF-------------------- 57

  Fly    63 SMRLLAGSGWTNNPGDLSSPLNVKHTTRSLSTEKQSTEAIYNKLADTESTTEDQTEITTVDHTDE 127
               |:..:||.|     ...|:|.|:...::.:.|||      :.|.|              .:.
  Fly    58 ---LIGRTGWVN-----VLDLDVLHSDNYVTVQHQST------VMDVE--------------PEP 94

  Fly   128 VVESSTSSPATGASKTETLYALEGNGKKYFVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRD 192
            :.|::.|.|                 |.:.|:|..|::...:|:.|.:...:|:..|..|.|...
  Fly    95 ITETNPSVP-----------------KGFLVYSNSCRIMEVDPYKNEVMRHFKRIKYKSCQKLTP 142

  Fly   193 MITVNYNVTDSTY----------------RLHKNENSTCCFKQILRAGTSANADHKYKLGPCVEF 241
            :..|.:......|                :||      ||:..:.|..     :.|.|...|..|
  Fly   143 LTQVKFEAKSQKYLLSIDGAAFGRYPVGKQLH------CCYMSVQRVD-----EMKVKYTKCQTF 196

  Fly   242 HQDFLVPTEVSAMITYCRR-------------PPFDKVSQKDAFSFVHPRKDQIENPTTPHRRRP 293
            ....|:|.....:|..|..             |..:.|.|:        .:...|.....::|.|
  Fly   197 KGSILLPDSAEGIIVKCDSGGRQIYINGHATVPVKEAVQQR--------LRMASEADAKGYQRPP 253

  Fly   294 SVLLWGIDSISRMNLELTMPRMYEYLNNQHWFELQGYNKMGDNTFPNLMAVLTGFNKTYANARCH 358
            |||:.|||||||:||...||:..:||.:..||||.||||:.||||||:||||||:|...|...|.
  Fly   254 SVLMLGIDSISRVNLIRAMPKTAQYLYDNGWFELAGYNKVDDNTFPNIMAVLTGYNLPNAMHACS 318

  Fly   359 PEKVRGLDACPFIWKDFKDKGYTTAFAEDWSKFSTFDYSSRGFFNPPTDVYGRPLVLAVEKELTI 423
            |..|.|||.|.:|||.::.:||.||:|||..|.:||:|..:||.|||.|.|.||.:.|.|.:|..
  Fly   319 PFVVGGLDKCDYIWKQYQQRGYVTAYAEDAVKINTFNYLKKGFKNPPADYYLRPYLSAAESQLDH 383

  Fly   424 LQRGQMPYCLGRKPASEYIYDMGVQFTMVNRNSTFFGMFWTNTFSHNDFSMPSAMDERMVKYMRT 488
            .....:.:|||...|:|::||.|::||....|.|:||.|||||.||:|.|..|:||..|.:|:|.
  Fly   384 TTVNGLVHCLGYLTAAEHVYDYGLEFTRRFLNETYFGFFWTNTHSHSDISQTSSMDSYMEEYLRK 448

  Fly   489 LDKNGIMDNTIIIFFSDHGSRFGPLRNLDSGFVEERLPFIYIRVPRWIREKYPKLLRNLQMNKNR 553
            |.:.|.|:||:::||||||.||||.|...||.:|||||.|:|.:|:.:|..:|:.:|:||:|:||
  Fly   449 LVRQGTMENTVVVFFSDHGMRFGPTRATWSGHLEERLPAIFIWLPQHLRRSHPQFVRSLQLNRNR 513

  Fly   554 LTSPYDIHATLRHILELD--TPKDKL-PRPDGCSSCHSVFEEVDWSRNCSQAGIEDHWCACNSFS 615
            ||:|||:|.|::|||.:.  ...:.| |.|| |..|.|:...|...|:||..||.||||.|..:.
  Fly   514 LTTPYDLHLTMKHILAISGRAEMESLGPAPD-CPQCQSLLTPVSPQRSCSDVGIADHWCTCWEYD 577

  Fly   616 DVPTTDPSARSMSTQLVEAINEYVAS-KKGT--KRCSRLKLNRISSVQRRGNS-------NRYLI 670
            .:.:|...:|.:..::|..:|.|||. :.||  |.|:.|.|:.|.|..|..::       :.|.:
  Fly   578 TISSTSKESRMLGKRVVSYLNNYVAEFRNGTFAKLCAPLSLHSIKSAFRAHHNALDPDEVHTYRL 642

  Fly   671 QLMAQPGDALFEATVDWDASAQRIPAQMPSISRLDTYAAKSRCSSVKETKKYCIC 725
            ..:..|....:|||:..:.:...:.. ..|:|||:.|:.::.|.:....||||.|
  Fly   643 IFVTSPNKGQYEATLRHNHTDDSVKV-TGSVSRLNVYSGEADCMNDFAAKKYCYC 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	200/510 (39%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	145/277 (52%)
CG7120	NP_001246667.1	DUF229	130..622	CDD:281053	200/511 (39%)
CG7120	NP_001246667.1	ALP_like	253..528	CDD:293745	143/274 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469409
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JJT
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27040
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860