DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15695 and CG3123

DIOPT Version :9

Sequence 1:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster
Sequence 2:	NP_608716.1	Gene:	CG3123 / 33478	FlyBaseID:	FBgn0031465	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	160/598 - (26%)
Similarity:	276/598 - (46%)	Gaps:	44/598 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 FVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRDMI--TV---NYNVTD-STYRLHKNENSTC 215
            ||::..|::|...|.:.......:....::|...:.|:  |:   ||.|.: |.:.:......:|
  Fly    51 FVNTTGCRISATKPLSLYALSFMEPIEPVLCRMEQLMVAETIGDRNYLVRNISRHGILSWRQVSC 115

  Fly   216 CFKQILRAGTSANADHKYKLGPCVEFHQDFLVPTEVSAMITYCRRPPFDKVSQKDAFSFVHPRKD 280
            .:::.:|...:.|.....|.....:..:...|.|.:..:.|:| ...|.::...|...|: |...
  Fly   116 IYREFVRVDDAHNKYISLKFFKLTDRTRYLEVGTGLQHIRTWC-WVDFGRIIFHDVMYFL-PPLP 178

  Fly   281 QIENPTTPHRRRP-SVLLWGIDSISRMNLELTMPRMYEYLNNQHWFELQGYNKMGDNTFPNLMAV 344
            |..|.:|.|::|. ||::.|:||||.|:......|:.:::.:....|..|||::..||:|||:.:
  Fly   179 QATNRSTEHQKRKLSVMILGVDSISHMHYMRYFHRVADFIEHLPHTEFWGYNRVALNTYPNLIPL 243

  Fly   345 LTGFNKTYANARCHPEKVRGLDACPFIWKDFKDKGYTTAFAEDWSKFSTFDYSSRGFFNPPTDVY 409
            ::|.:.:...|.|:.::: ..|.|.|:|.:||..||:|.||||......|.|..|||...|||:|
  Fly   244 VSGLSVSEMEASCYHDEL-NFDKCNFLWNEFKRAGYSTIFAEDTDTAGLFIYRKRGFQKQPTDIY 307

  Fly   410 GRPLVLAVEKELTILQRGQMPY-CLGRKPASEYIYDMGVQFTMVNRNSTFFGMFWTNTFSHNDFS 473
            .|||:..:|..  .|.|..... |.|.:...|:.||...:.........||...|.....|:.|.
  Fly   308 MRPLMTEIESH--SLYRTTFDLKCTGHRLYGEFYYDFVSKLIPHMERQLFFSFLWNMHGIHDVFP 370

  Fly   474 MPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGPLRNLDSGFVEERLPFIYIRVPRWIRE 538
            ....:|:..:..:..|.:.|:|:||:|:|..|||.||........|..|...|.:....|.|::.
  Fly   371 YAKFVDKDYLSILTRLHEKGVMENTLILFMGDHGLRFDKFARTAPGQHEMSQPLLIAIYPEWLKR 435

  Fly   539 KYPKLLRNLQMNKNRLTSPYDIHATLRHILELDTPKDK--------LPRPDGCSSCHSVFEEVDW 595
            ::|..:.|.:.|...|.:.:|:|.||:.::.||...|.        |....|.    |:|..:..
  Fly   436 RFPLAMSNFERNARSLITTFDLHETLKDVIHLDRLTDANVRNRTLYLTNERGI----SLFLPIPQ 496

  Fly   596 SRNCSQAGIEDHWCACNSFSDVPTTDPSARSMSTQLVEAINEYVASKKGTKRCSRLKLNRISSVQ 660
            :|||..|.|:.|:|.||....|.|.:.:.:..::..|:.|||.:   |...:|..|.|..:.:..
  Fly   497 NRNCKTAEIKQHYCLCNELKSVSTHESAIQEAASFAVDRINELI---KPYPQCRVLSLQSVRTAY 558

  Fly   661 R------RGN--SNRYLIQLMAQPGDALFEATV-----DWDASAQRIPAQMPSISRLDTYAAKSR 712
            |      |||  .::.:::|...|||..|:|||     :.:.:..::..   .::|.|.||.::.
  Fly   559 RAKSSTYRGNYRVSQVMVRLKTTPGDGNFDATVLITMLNGEKTDMKLGG---PVTRTDRYAHQAY 620

  Fly   713 CSSVKETKKYCIC 725
            |......:.||.|
  Fly   621 CVQNYRIEMYCYC 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	135/491 (27%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	85/279 (30%)
CG3123	NP_608716.1	DUF229	74..555	CDD:281053	135/492 (27%)
CG3123	NP_608716.1	ALP_like	192..468	CDD:293745	85/278 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JJT
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850