DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Synd and GRAP2

DIOPT Version :9

Sequence 1:NP_001262786.1 Gene:Synd / 42467 FlyBaseID:FBgn0053094 Length:495 Species:Drosophila melanogaster
Sequence 2:NP_001278753.1 Gene:GRAP2 / 9402 HGNCID:4563 Length:330 Species:Homo sapiens


Alignment Length:50 Identity:25/50 - (50%)
Similarity:33/50 - (66%) Gaps:1/50 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   443 KALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNGRVGLYPANYV 492
            :||||:|..|.|||.|..|:|.|.| |.....|..||::.::||:|||||
Human   277 RALYDFEALEDDELGFHSGEVVEVL-DSSNPSWWTGRLHNKLGLFPANYV 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SyndNP_001262786.1 F-BAR_PACSIN 17..272 CDD:153339
SH3_PACSIN 441..493 CDD:212777 24/49 (49%)
GRAP2NP_001278753.1 SH3_GRAP2_N 2..53 CDD:212880
SH2_Grb2_like 54..147 CDD:199828
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 143..244
SH3_GRAP2_C 275..327 CDD:212883 24/49 (49%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2056
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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