Protein Alignment Synd and PSTPIP1

DIOPT Version :9

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001308066.1
• Gene: PSTPIP1 / 9051
• HGNCID: 9580
• Length: 481
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 120/500 - (24%)
• Similarity: 194/500 - (38%)
• Gaps: 115/500 - (23%)

  Fly    15 DSFW-----EPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPE 74
            |:||     ....|:...:|:.||.|:|.|:::|:::||..|:.|.|.|...::|.|
Human    74 DAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAG-------- 130

  Fly    75 YGTTE-----AAWKGVLTESERISDVHMKIKDNLCNDVNS--QIKTWQKENYHHTLMQIKERKDL 132
             |.||     |::..:..:.|.:...|:::...|..::.|  :.:..|||          :||..
Human   131 -GQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKE----------QRKKY 184

  Fly   133 EDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQER-----NANADSSLSPDQVKKMHDRV 192
            |.:..:.||....|..|..::|..|...|   |.|.:.|:     :||....    ||:|..::.
Human   185 EAVMDRVQKSKLSLYKKAMESKKTYEQKC---RDADDAEQAFERISANGHQK----QVEKSQNKA 242

  Fly   193 QKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHS-CLDLT 256
            ::.||...:....|.|:||::.|..:.:.::..:..|..|..|..||...:..|: ||| .|.:.
Human   243 RQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALW-VHSNQLSMQ 306

  Fly   257 KVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPA 321
            .|:. .::|||...|:.......|:               .||::           .||....|.
Human   307 CVKD-DELYEEVRLTLEGCSIDADI---------------DSFIQ-----------AKSTGTEPP 344

  Fly   322 APITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAG 386
            ||:                |..|...:..:.|:|..........|......:..|...||.|.:.
Human   345 APV----------------PYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASA 393

  Fly   387 AATATAAATAASAASNRNSSVTNGNG--KVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYE 449
            |:|.|...|     ..||..|.....  ::..||....:|:                 :|||||.
Human   394 ASTETLTPT-----PERNEGVYTAIAVQEIQGNPASPAQEY-----------------RALYDYT 436

  Fly   450 GAESDELTFKQGDVFEK-LEDEDEQGWCKGRMNGRVGLYPANYVE 493
            ....|||....||:.|. ||.||  ||.....||:.|..|.:|:|
Human   437 AQNPDELDLSAGDILEVILEGED--GWWTVERNGQRGFVPGSYLE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	68/272 (25%)
		SH3_PACSIN	441..493	CDD:212777	22/52 (42%)
PSTPIP1	NP_001308066.1	F-BAR_PSTPIP1	81..322	CDD:153355	67/268 (25%)
		SH3_PSTPIP1	428..480	CDD:212758	23/70 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D727724at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920