Protein Alignment Synd and BZZ1

DIOPT Version :9

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_011982.1
• Gene: BZZ1 / 856514
• SGDID: S000001156
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 659
• Identity: 126/659 - (19%)
• Similarity: 230/659 - (34%)
• Gaps: 230/659 - (34%)

  Fly    22 NYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKW-------------GELIEKGP 73
            ::|.|.|.:::..|...|::|..:|||.:||.|::.|...|.::             |:.....|
Yeast    14 SFKETHKWVQNNLKWLKDIEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTP 78

  Fly    74 EYGTTEA----AWKGVLTESERISDVHMKIKDNLCNDVNSQIK--------TWQKEN-YHHTLMQ 125
              |:.||    ||..:|::::.||..|.::..:..|.|.:|:.        |..|.| :::.::.
Yeast    79 --GSIEAAGVVAWNEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVN 141

  Fly   126 IKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHD 190
            .|:                .:..::||||.||..||.|...|.|:...|      |.|:.||
Yeast   142 KKD----------------NIYHELEKAKKDYDEACSTMEMARNRYTKA------SNDRNKK--- 181

  Fly   191 RVQKTKDQVQKCREKY----EQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHS 251
            ::.:.:.::.||:.:|    .||.....||   |.:|:..|.:..|...:.:..|..::.....|
Yeast   182 KLDEKEMEMNKCKNEYLIKINQANRTKDKY---YFQDVPEVLDLLQDVNEAKTLFLNDLWLKAAS 243

  Fly   252 C-LDL-----TKVQSLPQIYEE----------FSHTINNADQQKDLKW-----WSNNHGINMAMN 295
            . .||     .::|:...:.::          ..|.:.|..:.:|..:     |.::....:
Yeast   244 VENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVWHDDEKFAV--- 305

  Fly   296 WPSFVEYTEEFR-DIAKG---------------------NKSKEALP------------------ 320
             ||.:| .|:.| .:||.                     ||.|..:.
Yeast   306 -PSSLE-VEDLRIKLAKAENDYNSLQDKTQNELSKLSTLNKIKHEMKTNEDNINATKFYDTLKEY 368

  Fly   321 ---AAPI----TLINQRPV-AEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSE 377
               .:|.    ||..|..| .|.:....|:...|..:...||....::.:.|:.   :.::...:
Yeast   369 LNVVSPFTSHETLKLQAEVQIESIQNNVPEEYDLSTDNIDLSKTKKKSGIFSKF---KHNILNVD 430

  Fly   378 AKTSAAVAGAATA--------------TAAATAASAASNR------NSSV----TNGNGKVDANP 418
            :|.|   :|.:|.              |:..|...:|.|.      |:|:    ||...|...|.
Yeast   431 SKPS---SGGSTGNGNGGPLHITSLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNS 492

  Fly   419 FDEEEE-------WDESDNVLVDNGE--------------------------------------- 437
            .|:.:.       ..:.|.:.:..|:
Yeast   493 SDDGKNKVLYAYVQKDDDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAAT 557

  Fly   438 ---------PGVP-----------VKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNG 482
                     |.||           ::|:|.||....||::...||:...:..:|..||..|..:|
Yeast   558 VKANDRGPAPEVPPPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYGECDG 622

  Fly   483 RVGLYPANY 491
            ..||:|.:|
Yeast   623 LKGLFPTSY 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	65/295 (22%)
		SH3_PACSIN	441..493	CDD:212777	18/62 (29%)
BZZ1	NP_011982.1	BAR	10..256	CDD:416402	63/271 (23%)
		SH3_CIP4_Bzz1_like	497..552	CDD:212711	2/54 (4%)
		SH3_Bzz1_2	581..631	CDD:212712	16/49 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.900