DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synd and LSB3

DIOPT Version :9

Sequence 1:	NP_001262786.1	Gene:	Synd / 42467	FlyBaseID:	FBgn0053094	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_219497.4	Gene:	LSB3 / 850580	SGDID:	S000002968	Length:	459	Species:	Saccharomyces cerevisiae

Alignment Length:	225	Identity:	51/225 - (22%)
Similarity:	84/225 - (37%)	Gaps:	65/225 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   334 EDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQS-------------------SVTTSEAK 379
            :|.:.:....|.:..:.|:..:.|:|.:.:|.....||                   |..:..|.
Yeast   233 DDYYDDDDYYNDIPSSFSSTDASSTRPNTRSTRRRAQSGSRYTFDDDDDDDDYGTGYSRNSRLAP 297

  Fly   380 TSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPF--DEEEEWDE--------------- 427
            |::..:|......:..::..||:|.|.......:...|.:  ||.:::|:
Yeast   298 TNSGGSGGKLDDPSGASSYYASHRRSGTAQSRARSSRNRWADDEYDDYDDDYESGYRRGNGRDRT 362

  Fly   428 SDNVLVD-------------------NGEPGVPVK---------ALYDYEGAESDELTFKQGDVF 464
            .|..:.|                   .|....|..         |||.:.|.||.:|.|::|||.
Yeast   363 KDREVDDLSNRFSKSRISSASTPQTSQGRFTAPTSPSTSSPKAVALYSFAGEESGDLPFRKGDVI 427

  Fly   465 EKLEDEDEQG-WCKGRMNGRVGLYPANYVE 493
            ..|:..|.|. |..||:|||.|::||||||
Yeast   428 TILKKSDSQNDWWTGRVNGREGIFPANYVE 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339
Synd	NP_001262786.1	SH3_PACSIN	441..493	CDD:212777	26/61 (43%)
LSB3	NP_219497.4	SYLF	1..219	CDD:225482
LSB3	NP_219497.4	SH3_Ysc84p_like	404..458	CDD:212776	27/54 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030