Protein Alignment Synd and pacsin3

DIOPT Version :10

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_005166650.1
• Gene: pacsin3 / 393964
• ZFINID: ZDB-GENE-040426-984
• Length: 435
• Species: Danio rerio
• Alignment Length: 497
• Identity: 200/497 - (40%)
• Similarity: 283/497 - (56%)
• Gaps: 70/497 - (14%)

  Fly     1 MSHHSDDQLLQAGS-DSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKK 64
            ||.:.|  |...|| ||||||||||||.|||:|||||||:|....||||.|||||::.|..|::|
Zfish     1 MSSNGD--LQDVGSWDSFWEPGNYKRTVKRIDDGYKLCNELVSCFQERAKIEKGYSQQLSDWARK 63

  Fly    65 WGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLM-QIKE 128
            |..::|||.:|||.|.||...:..::|:|::||::|:||..:.:.:|:.|||:.:|..:: ..:|
Zfish    64 WRGIVEKGSQYGTLEKAWHAFMNAADRLSEIHMELKENLVIEDSEKIRNWQKDAFHKQMIGGFRE 128

  Fly   129 RKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQ 193
            .||.::.|:||||||.:.|.:||..|..||||.|.||:|..:|.:|.||.:.|.|:|:|..||::
Zfish   129 TKDADEGFRKAQKPWVRKLKEVESTKKGYHSARKEERTALTRETHAKADPTKSQDEVRKFTDRLE 193

  Fly   194 KTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKV 258
            |...:.:|.:|:||:|:.|:.:.|..|:|||..|||..|..||.||.||||:|.::|..:||:..
Zfish   194 KCTQEAEKAKERYERALDELNRCNPRYMEDMEQVFEITQEAEKNRLCFFKEVLLDIHQHMDLSSN 258

  Fly   259 QSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEF-RDIAKGNKSKEALPAA 322
            .....:|.:...||:.|:..:||:||.|.||..|:||||.|.|::.|. |.|::  |.:.:....
Zfish   259 DRFRALYRDLGQTISAANDTEDLRWWRNTHGPGMSMNWPQFEEWSPEANRSISR--KDRNSRSDD 321

  Fly   323 PITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGA 387
            .:||.|.....::..|...:|....|:.|  |..|...|.|..||
Zfish   322 VVTLTNIVSAGDEPPQTLQETTRAGKDYS--SDWSDEESPKKYIA-------------------- 364

  Fly   388 ATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYEGAE 452
                                        ||..||||:            ..||.|:|||||.|.|
Zfish   365 ----------------------------ANGVDEEEK------------VVGVRVRALYDYTGQE 389

  Fly   453 SDELTFKQGDVFEKLEDEDEQGWCKGRM-NGRVGLYPANYVE 493
            :|||:||.|:...||.:|||||||||:: :|..||||||||:
Zfish   390 ADELSFKAGEELLKLGEEDEQGWCKGQLTSGEKGLYPANYVQ 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	116/255 (45%)
		SH3_PACSIN	441..493	CDD:212777	33/52 (63%)
pacsin3	XP_005166650.1	F-BAR_PACSIN3	16..273	CDD:153365	117/256 (46%)
		SH3	376..431	CDD:473055	35/54 (65%)