DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synd and rga8

DIOPT Version :9

Sequence 1:	NP_001262786.1	Gene:	Synd / 42467	FlyBaseID:	FBgn0053094	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_592988.2	Gene:	rga8 / 2542617	PomBaseID:	SPAC13A11.01c	Length:	777	Species:	Schizosaccharomyces pombe

Alignment Length:	330	Identity:	71/330 - (21%)
Similarity:	126/330 - (38%)	Gaps:	90/330 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLQAGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGP 73
            ::.:.|:.||.. :|....|::.|    |  |...::|...: |...|..:..::::||.:::
pombe     1 MISSFSNGFWSK-DYATGVKKLFD----C--LDNGVEENEQV-KNLLKLYKEANEEFGEKLQE-- 55

  Fly    74 EYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQIKERKDLEDLFKK 138
               .|:...||...|:........|..:.|.:::.:|.|           ..|:..||||.|
pombe    56 ---ITKECLKGKKPENTEDGATSNKAFEGLRSEIANQGK-----------QHIRIAKDLETL--- 103

  Fly   139 AQKPWAKLLAKVEKAKADYHSACKTERSA-TNQERNANADSSLSPDQVKKMHDRVQKTKD-QVQK 201
                   ::|...|...|:....:|.:.. |||.::           .:|.:..::|||. ...|
pombe   104 -------IIAPFSKMSIDHSQKLQTSQQVLTNQIKS-----------YEKKYYTLKKTKSAYYNK 150

  Fly   202 CR--EKYEQAIAEITKYNSVYIEDMTSVFEKCQT-------------FEKTRLQFFKEILFNVHS 251
            ||  |.||:...|..:..|..|.|:|:|....|.             |.:.|.:..||:|..|
pombe   151 CRNLEDYEEESKESNETTSEAITDLTTVSSPQQQSLLENDDDLIQLGFMEFRPEELKEVLAQV-- 213

  Fly   252 CLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNW-------PSFVEYTEEFRD- 308
                  :|.:|  .:::...|        |..:.|....|:.::|       |:.|. .|.|..
pombe   214 ------LQEIP--LQDYRVPI--------LGTYPNTCSGNIIVSWLQENLPVPTLVA-AEAFGQD 261

  Fly   309 -IAKG 312
             ||:|
pombe   262 LIAQG 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	58/271 (21%)
Synd	NP_001262786.1	SH3_PACSIN	441..493	CDD:212777
rga8	NP_592988.2	FCH	7..96	CDD:214492	21/112 (19%)
		DEP_fRgd2	205..287	CDD:239883	18/81 (22%)
		RhoGAP_fRGD2	452..654	CDD:239864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23065
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010