DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synd and rga9

DIOPT Version :9

Sequence 1:	NP_001262786.1	Gene:	Synd / 42467	FlyBaseID:	FBgn0053094	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001342903.1	Gene:	rga9 / 2542132	PomBaseID:	SPAC1952.16	Length:	670	Species:	Schizosaccharomyces pombe

Alignment Length:	413	Identity:	82/413 - (19%)
Similarity:	127/413 - (30%)	Gaps:	156/413 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SDSFWEPG---NYKRTTKRIEDGYKLCNDLQQLIQERAD--------IEKGYAK----------- 56
            |:|||...   ...|..:.|.:|.:....|.||:..||.        :.|.::|
pombe     6 SNSFWSRDYITGINRAQRLINEGVEQNEKLLQLLHIRAKSASSCSDLLFKSFSKFNKHHPLNEES 70

  Fly    57 --------------------SLR----------------TWSKKWGELIEKGPEYGTTEAAWKGV 85
                                ||.                .||||:...:::     ...||...:
pombe    71 NDLPSDAAIHQLYESYLMEASLHKKLGEQLNILVINPFANWSKKYSRRVDE-----IVSAAIVKI 130

  Fly    86 LTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQIKERKDL--------EDLFKKAQKP 142
            ...:.|.|.|:.| |.||.:  ...|.|.:|.|...:|.....:.|:        :.|......|
pombe   131 NNYNSRFSHVNSK-KSNLTD--RKPIPTSRKSNKSDSLASALSQLDINPSNVNKFDGLINIVDHP 192

  Fly   143 W-----AKLLAKVEKAK----------ADYH---------SACKT----ER-----SATNQ---- 170
            :     |.:|.|:.||.          .||.         .|.||    |:     .|.||
pombe   193 YTAEEFANVLLKLMKASTVKRKSYSHLGDYELVTNCSLLFEAIKTTFGLEKDSYVVKAGNQLIQH 257

  Fly   171 ------------ERNANAD----------------SSLSPDQVKKMHDRVQKTKDQ--VQKCREK 205
                        |.:...|                |.|..|...:::|.:..|.|.  :||....
pombe   258 GLIRLLGIRRVFENDPEIDAQFTTKSQQLLKSYHLSILEVDPYFQVNDPITATNDDPVLQKYNLA 322

  Fly   206 Y---EQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTK--VQSLPQIY 265
            |   ||...|:..|       :..||:..:..|..||...|.:|.   .|.:.:.  :.||..|:
pombe   323 YDNLEQCRHELELY-------LFMVFKDLEQAELDRLNAVKSVLV---ECSNYSGNFIPSLNSIF 377

  Fly   266 EEFSHTINNADQQKDLKWWSNNH 288
            .:..::..|.|..:|:....|.|
pombe   378 IDNLNSFKNLDSLRDMSTQINKH 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	75/392 (19%)
Synd	NP_001262786.1	SH3_PACSIN	441..493	CDD:212777
rga9	NP_001342903.1	RhoGAP	422..625	CDD:295372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23065
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100