DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synd and Sh3yl1

DIOPT Version :9

Sequence 1:	NP_001262786.1	Gene:	Synd / 42467	FlyBaseID:	FBgn0053094	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_038737.1	Gene:	Sh3yl1 / 24057	MGIID:	1346118	Length:	340	Species:	Mus musculus

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	78/196 - (39%)	Gaps:	43/196 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 YTEEFR--DIAKGNKSKEALPAAPITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKS 364
            |.::.|  ||..|:             :.|...|||:::      .|...|....:...|.::|
Mouse   180 YCQDIRAYDILFGD-------------VPQPAQAEDLYE------ILNSFTEKYETEGQRINLK- 224

  Fly   365 EIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESD 429
            ::|..|........|.|:....|  .......|.:..|||          :...:.|...:.|..
Mouse   225 KVAREQRKAKELPPKPSSRPQPA--HPPVQLNAGSQGNRN----------EYKLYPELSSYHEKT 277

  Fly   430 NVLVDNGEPGVPVKALYDYEGAESDELTFKQGD---VFEKLEDEDEQGWCKGRMNGRVGLYPANY 491
            ..|   .:| :.|.|||.:||.:..:|.|:.||   |..|.:...:  |.:|::.|:.|::||||
Mouse   278 GNL---NQP-IEVTALYSFEGQQPGDLNFQAGDRIIVISKTDSNFD--WWEGKLRGQTGIFPANY 336

  Fly   492 V 492
            |
Mouse   337 V 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339
Synd	NP_001262786.1	SH3_PACSIN	441..493	CDD:212777	21/55 (38%)
Sh3yl1	NP_038737.1	SYLF_SH3YL1_like	11..209	CDD:211401	10/47 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	226..259		6/34 (18%)
		SH3_SH3YL1_like	285..338	CDD:212775	21/55 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030