Protein Alignment Synd and sdpn-1

DIOPT Version :9

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001367622.1
• Gene: sdpn-1 / 181058
• WormBaseID: WBGene00018467
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 154/499 - (30%)
• Similarity: 266/499 - (53%)
• Gaps: 47/499 - (9%)

  Fly    17 FWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAA 81
            |||.|:||...||.:||.:..:|..::.:|||:||..|:|.|...::||...:::....|:.:..
 Worm    16 FWEVGSYKHNVKRFKDGVEQLDDYCKMSRERAEIEAKYSKMLSQHAEKWRAHVDRTVSAGSVKTV 80

  Fly    82 WKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQ-IKERKDLEDLFKKAQKPWAK 145
            |..::.|:..:|.||..:||.|.:|:.::..|::|.:.|.::.: .||.:::||.|:||||||.|
 Worm    81 WNELIGEATALSRVHNSLKDCLIDDIVNETTTYRKNSLHTSVFKGPKEIREIEDHFEKAQKPWKK 145

  Fly   146 LLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAI 210
            |:.|:|..:..|::.|:.|:||....:|...|:|:|||...|..:|.:|.|::||:.:..|::.:
 Worm   146 LVDKMEDKRGKYYNVCRQEKSALVNLQNCQTDTSVSPDAATKFRERHEKLKEEVQRTKVDYQKTL 210

  Fly   211 AEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNV-HSCLDLTKVQSLPQIYEEFSHTINN 274
            ..:.:|.:||:|.|..||:.||..|..|.||...|:... ....::.:...:..::::...:|.:
 Worm   211 TNLNEYKNVYMEAMAHVFKMCQEKEMDRSQFLIGIVQKTQRHYANIIRNSQMSGLHQQLEQSIRS 275

  Fly   275 ADQQ---KDLKWWSNNHGINMAMNWPSFVEYTEEFRDI-AKGNKSKEALPAAPITLINQRPVAED 335
            ||.:   :||..||:.:|::....|||||||:.|.|:| |:|..:|:   |..:.|..|...:||
 Worm   276 ADSEAVKRDLAQWSSVNGVDAFSEWPSFVEYSPEIRNIAARGGSTKD---AGGVILTRQINRSED 337

  Fly   336 VHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAA 400
            :    |.|:|     :||.||:...:...|.....|..::||:.||         |..:...::.
 Worm   338 I----PSTHS-----NTLPSVAVNTASSHEDVGKSSPKSSSESDTS---------TFDSRKHNST 384

  Fly   401 SNRNSSVTNGNGKVDANPFDEEEEWDESD--------NVLVDNGEPG--------VPVKALYDYE 449
            :|:..:......::...|..    |..||        ....|:.:.|        .|...||||.
 Worm   385 ANKYKNQPQNTTQIQPPPVG----WHPSDGPDSPPLSTETPDSAKYGDFEEFTTSKPAVVLYDYA 445

  Fly   450 GAESDELTFKQGDVFEKLEDEDEQGWCKGRMNGRVGLYPANYVE 493
            .||.||:..::|::.|.|.:.|..|||.||::|.|||:||:||:
 Worm   446 PAEGDEIALRKGEMIEVLTEPDSLGWCTGRVSGNVGLFPASYVQ 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	81/256 (32%)
		SH3_PACSIN	441..493	CDD:212777	25/51 (49%)
sdpn-1	NP_001367622.1	F-BAR_PACSIN	16..273	CDD:153339	81/256 (32%)
		SH3	437..489	CDD:418401	25/51 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166819
Domainoid	1	1.000	158	1.000	Domainoid score	I2526
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21414
Inparanoid	1	1.050	260	1.000	Inparanoid score	I1919
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54548
OrthoDB	1	1.010	-	-		D432948at33208
OrthoFinder	1	1.000	-	-		FOG0001073
OrthoInspector	1	1.000	-	-		oto19992
orthoMCL	1	0.900	-	-		OOG6_104815
Panther	1	1.100	-	-	LDO	PTHR23065
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	1	1.000	-	-		X728
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940