Protein Alignment Synd and Fnbp1

DIOPT Version :9

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_006497754.1
• Gene: Fnbp1 / 14269
• MGIID: 109606
• Length: 649
• Species: Mus musculus
• Alignment Length: 645
• Identity: 114/645 - (17%)
• Similarity: 212/645 - (32%)
• Gaps: 186/645 - (28%)

  Fly    18 WEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKW--GELIEKGPEYGTTEA 80
            |:  .:....|..:.|..:.....:.::||.:||..|||.||..|||:  .:..::..||..|..
Mouse     8 WD--QFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTAC 70

  Fly    81 -AWKGVLTESERISDVHMKIKDNLCNDVN-------SQIKTWQKENYHHTLMQIKERKDLEDLFK 137
             |:...|.|....:..|..|.:|:.:.:.       .::|..:|.|:|..              :
Mouse    71 KAFLSTLNEMNDYAGQHEVISENMTSQITVDLMRYVQELKQERKSNFHDG--------------R 121

  Fly   138 KAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKC 202
            |||:.......::|.:|..:...||....|.......:||.:::...|:|...:.|..:...:..
Mouse   122 KAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRQQMAEDS 186

  Fly   203 REKYEQAIAEITKYN-SVYIEDMTSVFEKCQTFE-----------KTRLQFFKEILFNVHSCLD- 254
            :..|...:....:.. ..|...:.::|:|.|..|           ||..:..::::..:..|||
Mouse   187 KADYSLILQRFNQEQWEYYHTHIPNIFQKIQEMEERRIVRIGESMKTYAEVDRQVIPIIGKCLDG 251

  Fly   255 -LTKVQSLPQ---------------------IYEEFSHTI------NNADQQKDLKWWSNNHGIN 291
             :...:|:.|                     .:|:::..:      |:....|:.|......|.:
Mouse   252 IVKAAESIDQKNDSQLVVEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSSSKEGKPELRFGGKS 316

  Fly   292 MAMNWP----------------------------------------------SFVEYTEE----- 305
            ....||                                              .|.|:...
Mouse   317 RGKLWPFIKKNKLMSLLTSPHQPPPPPPASASPSAVPNGPQSPKQPKEPLSHRFNEFMTSKPKIH 381

  Fly   306 -FRDIAKGNKS----KE-----------ALPAAPITLINQRPVAEDVHQEYPQ------------ 342
             ||.:.:|.:|    ||           ||.|....|..:..|..:....:|.
Mouse   382 CFRSLKRGTQSLCYHKELMKRTLGKPTHALEARDYVLSLKLGVTPEDFSNFPPEQRRKKLQQKVD 446

  Fly   343 --TNSLKKNTSTLSSVSSR-------------ASVKSEIATTQSSVTTSEAKTSAAVAGAATATA 392
              ...::|.|....:::..             ||:..::.....::.....:.....|..|....
Mouse   447 DLNREIQKETDQRDAITKMKDVYLKNPQMGDPASLDQKLTEVTQNIEKLRLEAQKFEAWLAEVEG 511

  Fly   393 AATAASAASNRNS---------SVTNGNGKVDANP---FDEEEEWDESDNVLV-------DNGEP 438
            ...|.|..:.|.|         :|||.....:::|   :.||:..:....||.       |:.||
Mouse   512 RLPARSEQARRQSGLYDGQTHQTVTNCAQDRESSPDGSYTEEQSQESEHKVLAPDFDDEFDDEEP 576

  Fly   439 GVPV----KALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMN-GRVGLYPANYVE 493
             :|.    ||||.:||.....::..:|:....:|::...||.:.|.| ...|..|.:|||
Mouse   577 -LPAIGTCKALYTFEGQNEGTISVVEGETLSVIEEDKGDGWTRIRRNEDEEGYVPTSYVE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	55/298 (18%)
		SH3_PACSIN	441..493	CDD:212777	16/56 (29%)
Fnbp1	XP_006497754.1	F-BAR_FBP17	5..257	CDD:153360	52/264 (20%)
		HR1	434..510	CDD:381797	6/75 (8%)
		SH3_FBP17	581..637	CDD:213004	17/55 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940