DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synd and pstpip2

DIOPT Version :9

Sequence 1:	NP_001262786.1	Gene:	Synd / 42467	FlyBaseID:	FBgn0053094	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_009303409.1	Gene:	pstpip2 / 100537857	ZFINID:	ZDB-GENE-091204-90	Length:	331	Species:	Danio rerio

Alignment Length:	324	Identity:	72/324 - (22%)
Similarity:	131/324 - (40%)	Gaps:	56/324 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DSFW-----EPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPE 74
            |:||     ....|....:.:.||.:.|.:::..::.||.||:.|||.|...|||    :....|
Zfish     8 DNFWNTDITSTAGYDTIIQHLNDGKRTCKEIEDFMKARAAIEEKYAKELLGLSKK----VCGHSE 68

  Fly    75 YGTTEAAWKGVLTESERISDVHMKIKDNLCNDVN--SQIKTWQKENYHHTLMQIKERKDLEDLFK 137
            ..|.:.:......::|.:|..|:.:...:..:..  ...:..|||          .||.:|....
Zfish    69 MNTLKRSLDVFKLQTENMSLSHLHLAQTMREEAKKLEDFREKQKE----------ARKKVEQQMD 123

  Fly   138 KAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKC 202
            ...|..|....|..:||..|...|: ::..|.|..|.:| ::.|..|.:|::.:.|:.|...::.
Zfish   124 ALHKQKAAQYKKTAEAKKSYDQKCR-DKEETEQNMNRSA-TTCSAKQQEKLYAKTQQAKQAAEEA 186

  Fly   203 REKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEK---TRLQFFKEILFNVHSCLDLTKVQSLPQI 264
            ...|.|.::.:.|....::.:..   :.|:.|||   .|:...:.|::...:.|....|.| .:|
Zfish   187 DRIYSQNVSVLGKMREEWLNEHV---KACEFFEKQEVERINTLRNIVWTHLNHLSQQCVSS-DEI 247

  Fly   265 YEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLIN 328
            |||...::...:.|:|::     |.:|:...                |:|     |.|||...|
Zfish   248 YEEVRKSLEQCNIQEDIE-----HFVNLRRT----------------GDK-----PPAPIPYEN 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	60/264 (23%)
Synd	NP_001262786.1	SH3_PACSIN	441..493	CDD:212777
pstpip2	XP_009303409.1	BAR	15..253	CDD:299863	58/257 (23%)
pstpip2	XP_009303409.1	T3SSipB	55..192	CDD:293143	32/152 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D727724at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920