Protein Alignment Synd and pacsin3

DIOPT Version :10

• Sequence 1: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001123383.1
• Gene: pacsin3 / 100038179
• XenbaseID: XB-GENE-493382
• Length: 457
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 196/491 - (39%)
• Similarity: 278/491 - (56%)
• Gaps: 60/491 - (12%)

  Fly    14 SDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTT 78
            |.||||.|||::|.||||||.:|||||....:|||.|||.||:.|..||.||...:||||:|||.
 Frog    12 SGSFWEAGNYRQTVKRIEDGNRLCNDLVSCFRERAKIEKSYAQQLSDWSNKWRTSLEKGPQYGTL 76

  Fly    79 EAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLM-QIKERKDLEDLFKKAQKP 142
            |.:|:..||.:|::|::|.::::.|.::.:.:::.||||.:|..:: ..:|.|:.|:.|.|||||
 Frog    77 EKSWQAFLTAAEKLSEIHTELRNQLWDEDSGKVRDWQKEAFHKQMIGGFRESKEAEESFSKAQKP 141

  Fly   143 WAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYE 207
            |.|.|..||.||..||.|.|.||:|..:|.::.|||::|.:|::|:.|||:|...:..|.:..||
 Frog   142 WVKKLKDVEVAKKRYHVARKDERAAQVREDHSKADSTVSQEQLRKLRDRVEKCNQEADKTKGVYE 206

  Fly   208 QAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTI 272
            :|:.|:.:||..|:|||...||.||..|:.||.||||:|.:.|..|||:...|...:.::...:|
 Frog   207 KALEELNRYNPRYMEDMEQAFESCQEAEQKRLCFFKEMLLDFHKHLDLSSKDSFHVLNKDLHQSI 271

  Fly   273 NNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEF-RDIAKGNKSKEALPAAPITLINQRPVAEDV 336
            ..||.|:|||||.|.||.:||||||.|.|::.|. |.|:|..:|.:.:  ..:||....|..:.|
 Frog   272 QTADDQQDLKWWRNTHGPSMAMNWPQFEEWSPETQRTISKKERSNKNV--EEVTLTGILPARDGV 334

  Fly   337 HQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAAS 401
            ....|        |..|:...|......:...|.:....|:
 Frog   335 SAGTP--------TQQLNRGFSYTDEDQDFYATLTDTPHSD------------------------ 367

  Fly   402 NRNSSVTNGNGKVDANPFDEEEEWDESDN---VLVDNGE-----PGVPVKALYDYEGAESDELTF 458
                     .||.||:      ||.|.|:   .:..||.     .||.|:|||||.|.|:|||:|
 Frog   368 ---------TGKDDAS------EWSEDDSPKKSMDSNGREVSQVEGVRVRALYDYAGQEADELSF 417

  Fly   459 KQGDVFEKLEDEDEQGWCKGR-MNGRVGLYPANYVE 493
            ..|:...|:..|||||||:|| ::||:|||||||||
 Frog   418 TAGEELMKIGSEDEQGWCRGRLLSGRIGLYPANYVE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	113/255 (44%)
		SH3_PACSIN	441..493	CDD:212777	32/52 (62%)
pacsin3	NP_001123383.1	F-BAR_PACSIN3	15..272	CDD:153365	113/256 (44%)
		SH3_PACSIN3	398..453	CDD:212930	34/54 (63%)