Protein Alignment Adss and ADSS1

DIOPT Version :10

• Sequence 1: NP_650918.1
• Gene: Adss / 42466
• FlyBaseID: FBgn0027493
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: XP_011534714.1
• Gene: ADSS1 / 122622
• HGNCID: 20093
• Length: 501
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 237/395 - (60%)
• Similarity: 303/395 - (76%)
• Gaps: 6/395 - (1%)

  Fly    57 QGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKNEAKGLQHLENRL 121
            :||||||||||.:|.|:||||||||::|.|.||.||||||||||.||:|..|||.|||:..|.||
Human   107 RGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRL 171

  Fly   122 IISDRAHLVFDFHQH-VDGMQEAEK---GGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNLF 182
            ||||||||.....|. |||:||.::   .||::|||||||||.|||||.|.|:|:.:||.||:.|
Human   172 IISDRAHLGDSGQQEAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEF 236

  Fly   183 SEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRN-GKTILVEGANA 246
            |.:||::...|..:||::.:|:|.:|.|.|.:|:::||.|:|.:.|::.||.. .|.||||||||
Human   237 SSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANA 301

  Fly   247 AMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLL 311
            |:|||||||||:||||||::|||.||||:|||.||:|.|||||||||||.|.|||||:|:||.||
Human   302 ALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLL 366

  Fly   312 QTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKL 376
            ||||.|.||||.|||||||||:.:|:|..:|||:|.:.||||||||.|.|:||.|:||. ||:::
Human   367 QTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKL-NGKRI 430

  Fly   377 DHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFLESELSVPVRWVGVGKGRE 441
            .:||.....|..:||||..||||:..|...|.:::||..||:|:||:|:.:.|.|:||||||.||
Human   431 PYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRE 495

  Fly   442 SIINV 446
            |:|.:
Human   496 SMIQL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adss	NP_650918.1	Adenylsucc_synt	28..444	CDD:459912	236/391 (60%)
ADSS1	XP_011534714.1	Adenylsucc_synt	108..498	CDD:459912	236/390 (61%)