DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syp and rbm46

DIOPT Version :9

Sequence 1:	NP_001262777.1	Gene:	Syp / 42460	FlyBaseID:	FBgn0038826	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001072501.1	Gene:	rbm46 / 779956	XenbaseID:	XB-GENE-1011216	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	501	Identity:	192/501 - (38%)
Similarity:	271/501 - (54%)	Gaps:	92/501 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 ILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRL 237
            :::.||||:....||||:|||||.|||..|..|||||.||||:|||||:|:|||...|.|::.||
Frog    28 LIDNTGYTMVQVNGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDKLVPLFARAGKIYEFRL 92

  Fly   238 MMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDE 302
            ||: .:|.|||||||.:||:|.|:.|:|.||::||..||.|||.:|.:|.|||:|:||:.:.::|
Frog    93 MME-FSGENRGYAFVMYTNKEEALLAIRMLNNYEICQGKFIGVCVSLDNCRLFIGSIPQEKRKEE 156

  Fly   303 LIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWA 367
            ::||..|...|:.:||:|.|..||.|||||.|:.||||:||::|:|:|..|..::||..|.|.||
Frog   157 ILEEMKKVTEGVMDVIVYPSATDKTKNRGFAFVMYESHRAAAMARRKLIPGPFQLWGHTIKVAWA 221

  Fly   368 DPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQY--GKVERVKKIKDYAFIHFEDRDSAVE 430
            .|::|.||:||.||||||||||....:|:.:|.:|.:|  |.|||||||:||||:||..||.|:.
Frog   222 SPEKEVDEETMQKVKVLYVRNLMMSTTEETIKAEFNRYKPGVVERVKKIRDYAFVHFFRRDYAIA 286

  Fly   431 AMRGLNGKEIGASNIEVSLAKPPSDK-----------KKKEEIL-----RARERRMMQMMQARPG 479
            ||..:||:.|..:.|||:||||.:.:           ....|.|     :...::.:.|....|.
Frog   287 AMSVMNGRLIDGARIEVTLAKPVNKEAAWRQNGNGHMNANSECLLNFANKEGSQKALDMCSNVPA 351

  Fly   480 IVGFETLSPYRNLSPTHPSIMS----LTPMRPGARMPLRTPI-------------PREYDYFY-- 525
                     |.| :|..|:.:.    ..|..||.::   |||             ....:||.
Frog   352 ---------YLN-NPNSPTFLEPETCTYPCIPGTKL---TPINLYSLKIHHFHSAVMHLEYFCYK 403

  Fly   526 ------DFFGFSDYRQGGSF------------GNNVSYY--DDMYRWIDG-------------DY 557
                  :::.:|...|.|..            ||..||:  |.:..:::.             ||
Frog   404 NNWSFPEYYLYSTTGQDGKMLLAYKVILPAITGNTNSYFMPDKLCSFVEDAKELAAQFTLMHLDY 468

  Fly   558 NYYDYPNGGGGGSGGGGGSVSGG------TVLPLSAGGSQNSPMAS 597
            :|  :|..|...|.....:.||.      |..|.|.....:||..|
Frog   469 SY--HPTSGKNISLPSTAATSGTSGVLPYTPKPYSYSSYPSSPNVS 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	RRM1_hnRNPR_like	205..283	CDD:240695	47/77 (61%)
		RRM2_hnRNPR_like	286..367	CDD:240696	38/80 (48%)
		RRM3_hnRNPR_like	381..452	CDD:240697	40/72 (56%)
rbm46	NP_001072501.1	hnRNP-R-Q	20..495	CDD:273732	186/482 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384330at2759
OrthoFinder	1	1.000	-	-		FOG0000581
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X331
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920