Protein Alignment Syp and A1cf

DIOPT Version :9

• Sequence 1: NP_001262777.1
• Gene: Syp / 42460
• FlyBaseID: FBgn0038826
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001074543.1
• Gene: A1cf / 69865
• MGIID: 1917115
• Length: 595
• Species: Mus musculus
• Alignment Length: 634
• Identity: 230/634 - (36%)
• Similarity: 311/634 - (49%)
• Gaps: 119/634 - (18%)

  Fly   167 EDKIKKILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGI 231
            |..::.:::||||:|....||||||||||.|:...|..|||:|.||:|:|::|||||||.|..|.
Mouse    17 EAALRALVQRTGYSLVQENGQRKYGGPPPGWDSTPPERGCEIFIGKLPRDLFEDELIPLCEKIGK 81

  Fly   232 IWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPK 296
            |:::||||| ..|.|||||||||:|::.|.||::|||::|||||:.:||..|.:|.|||||.|||
Mouse    82 IYEMRLMMD-FNGNNRGYAFVTFSNKQEAKNAIKQLNNYEIRTGRLLGVCASVDNCRLFVGGIPK 145

  Fly   297 NRDRDELIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCD 361
            .:.|:|::.|..|...|:.:||:|.|..||.|||||.|:|||||:||::|:|||..|||::||..
Mouse   146 TKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRRLLPGRIQLWGHP 210

  Fly   362 IIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQY--GKVERVKKIKDYAFIHFED 424
            |.||||:|:.|.||.|||.||:||||||....||:.::::|...  |.|||||||:||||:||.:
Mouse   211 IAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNSIKPGAVERVKKIRDYAFVHFSN 275

  Fly   425 RDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERR--MMQMMQARP--------- 478
            |:.|||||:.||||.:..|.|||:||| |.||.......|....|  |:|.....|
Mouse   276 REDAVEAMKALNGKVLDGSPIEVTLAK-PVDKDSYVRYTRGTGGRNTMLQGEYTYPLSHVYDPTT 339

  Fly   479 ---GIVGFETLSPYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFG 540
               |...|.|...|..:...|   ...|......|..:|||..||.
Mouse   340 TYLGAPVFYTPQAYAAIPSLH---FPATKGHLSNRALIRTPSVREI------------------- 382

  Fly   541 NNVSYYDDMYRWIDGDYNYYDYPNG-----GGGGSG-------GGGGSVSGG-------TVLPLS 586
                              |.:.|.|     |.||.|       |.|..|.|.       .:||
Mouse   383 ------------------YMNVPVGAAGVRGLGGRGYLAYTGLGRGYHVKGDKREDKLYDLLP-- 427

  Fly   587 AGGSQNSPMASGQRSARGSASGPSASPSL--------------MGVGRG------HGITVPRGRV 631
              |.:.:||.:.....:|....|.....:              ..:|:.      :.:|:|  .:
Mouse   428 --GMELTPMNTVSLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKVTIP--AL 488

  Fly   632 VGQRGSI-----SRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPAATGGFRGVLP--TRPS 689
            ..|..:|     .:|.|........||....|......:.|..|..||.||..  .|.|  ..||
Mouse   489 ASQNPAIHPFIPPKLSAYVDEAKRYAAEHTLQTLGIPTEGGDAGTTAPTATSA--TVFPGYAVPS 551

  Fly   690 ARGTQHVKPLQNLPVVGKRKFDGGHQNPADVKRRYPS-GLIGNGGSWGS 737
            |........|:....:|:   |.......:|   ||: .|...|.::|:
Mouse   552 ATAPVSTAQLKQAVTLGQ---DLAAYTTYEV---YPTFALTTRGDAYGT 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	RRM1_hnRNPR_like	205..283	CDD:240695	47/77 (61%)
		RRM2_hnRNPR_like	286..367	CDD:240696	45/80 (56%)
		RRM3_hnRNPR_like	381..452	CDD:240697	41/72 (57%)
A1cf	NP_001074543.1	hnRNP-R-Q	2..595	CDD:273732	230/634 (36%)
		Required for nuclear localization. /evidence=ECO:0000250|UniProtKB:Q9NQ94	360..409		15/88 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384330at2759
OrthoFinder	1	1.000	-	-		FOG0000581
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X331
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820