DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syp and rbm46

DIOPT Version :9

Sequence 1:	NP_001262777.1	Gene:	Syp / 42460	FlyBaseID:	FBgn0038826	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001073493.2	Gene:	rbm46 / 566042	ZFINID:	ZDB-GENE-061013-298	Length:	523	Species:	Danio rerio

Alignment Length:	315	Identity:	162/315 - (51%)
Similarity:	221/315 - (70%)	Gaps:	11/315 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 RASQQGVAAPATVKGPDEDK---IKKILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCG 211
            |:||     |:.....|..|   :..:::||||::....||||:|||||.|||..|..|.|||.|
Zfish     4 RSSQ-----PSDNSRMDSSKEAALLALMDRTGYSMVQENGQRKFGGPPPGWEGPPPPRGREVFVG 63

  Fly   212 KIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGK 276
            |||:|||||||:|:||..|.|::.||||: .:|.|||||||.:|.||.|..|::.|:::|||.||
Zfish    64 KIPRDMYEDELVPVFEQAGHIYEFRLMME-FSGENRGYAFVMYTTREKAQRAIQLLDNYEIRPGK 127

  Fly   277 KIGVTISFNNHRLFVGNIPKNRDRDELIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHK 341
            .|||.:|.:|.|||:|:|||::.::|:.||..|...|:.:||:|.|..|:.|||||.|:||||||
Zfish   128 FIGVCVSLDNCRLFIGSIPKDKKKEEIQEEMMKVTEGVMDVIVYPSAVDRMKNRGFAFVEYESHK 192

  Fly   342 AASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQY- 405
            ||::|:|:|..|..::||..|.||||:|::|.||:||.:|:|||||||....:|:.|:.:|.|.
Zfish   193 AAAMARRKLIPGTFQLWGHTIQVDWAEPEKELDEETMQRVRVLYVRNLMLSTTEETLRSEFSQLK 257

  Fly   406 -GKVERVKKIKDYAFIHFEDRDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKK 459
             |.||||||:.|||||||.:|:.|:.|:..:|||.|..|.|||:||||.|....|
Zfish   258 PGSVERVKKLTDYAFIHFYNREDALTALESMNGKVIDGSPIEVTLAKPASKDGNK 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	RRM1_hnRNPR_like	205..283	CDD:240695	46/77 (60%)
		RRM2_hnRNPR_like	286..367	CDD:240696	41/80 (51%)
		RRM3_hnRNPR_like	381..452	CDD:240697	39/72 (54%)
rbm46	NP_001073493.2	RRM1_RBM46	58..134	CDD:240928	45/76 (59%)
		RRM2_RBM46	136..220	CDD:240936	43/83 (52%)
		RRM_SF	225..305	CDD:302621	43/79 (54%)
		DND1_DSRM	392..463	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384330at2759
OrthoFinder	1	1.000	-	-		FOG0000581
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X331
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820