Protein Alignment Syp and Raver2

DIOPT Version :10

• Sequence 1: NP_001262777.1
• Gene: Syp / 42460
• FlyBaseID: FBgn0038826
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_038966220.1
• Gene: Raver2 / 362551
• RGDID: 1307610
• Length: 785
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 140/670 - (20%)
• Similarity: 222/670 - (33%)
• Gaps: 199/670 - (29%)

  Fly   157 AAPATVKGPDEDKIKKILE---RTGYTLDVTTGQRKYGGPPPH------------WEGN------ 200
            |.|.:..||...:....|.   |:|.: :...|:|:.||....            |:|.
  Rat   100 ARPCSASGPPRPRAASPLSLPLRSGLS-ESAAGRREDGGAGRRRGGPGLGIRTLCWDGGGGRGAR 163

  Fly   201 ----------VPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFT 255
                      .||.||.........:..|       ||.|        ..|..|.... ||||..
  Rat   164 AAPGGGGCAAPPGGGCTAAADATGAEQPE-------ENPG--------EKPAPGQQLP-AFVTLL 212

  Fly   256 NREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDELIEEFSK--HAPGLYE-- 316
            |.|.|.:|:::.:.|..| |:::.|.:...:..|.:.|:|.:    ..:|||.:  .|.|..|
  Rat   213 NGEQAQSAIQRFHQFSFR-GRELTVQLQPTDALLCITNLPVS----FTLEEFEELVRAYGNIERC 272

  Fly   317 VIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKV 381
            .::||......|  |:.|:||.....|:.|:..| .|| ::....:...|.|......|...|
  Rat   273 FLVYSEVTGHSK--GYGFVEYMKKDFAAKARLEL-LGR-QMGASALFAQWMDVNLLASELIHS-- 331

  Fly   382 KVLYVRNLTQDVSE-DKLKEQFEQYGKVERVKKIKD-------YAFIHFEDRDSAVEAMRGLNGK 438
            |.|.:..|..|.|: ::|.:.|....|....:..:|       :|.:.:...:.|.|..:..:|.
  Rat   332 KCLCIDKLPSDYSDSEELLQLFSSIHKPVFCQLAQDEGSHGGGFAVVEYSTAEHAEEVQQVADGI 396

  Fly   439 EIGASNIEVSLAKPPSDKKKKEEILRARERRM-------------MQMMQA-----------RPG 479
            .|..|.:::|...|.:..:.....|.|.:|.|             :|:|::           :|.
  Rat   397 TIKGSQVQLSFCAPGAPGRSTLAALIAAQRAMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ 461

  Fly   480 IVGFETLSPYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFGNNVS 544
            :.| ..:.|...::|:...::|  |..|.|                 ...||..:|..:.||..|
  Rat   462 LCG-RAVKPVLGVTPSLSHLLS--PSLPSA-----------------LLHFSKAQQSSAVGNTSS 506

  Fly   545 YYDDMYRWIDGDYNYYDYPNGGGGGSGGGGGSVSGGTVLPL--------SAGGSQNSPMASGQRS 601
            ..                              :...:.|||        ....:.|.|...|:..
  Rat   507 LL------------------------------LQNLSPLPLIQQPLMKFDNAHTNNKPGLLGEPP 541

  Fly   602 AR----GSASGPSASPSLMGVGRGHGITVPRGRVVGQRGSISRLGAQTVPQAAGAAA-------- 654
            |.    ..|.||   |..:....||.         |:....|.|.|.....|||...
  Rat   542 AMVLQPALAIGP---PLPLKTDLGHH---------GEAHKTSNLIASQTTLAAGLGVLPFFPHQL 594

  Fly   655 AAGQAAAAVAQRGAT--GQGAPAATGGFRGVLPTRPSARGTQHVKPLQNL-------PVVGKRKF 710
            .||||...   ||.|  .|.||.::        :..|..|:||.  ||..       |:.|.:|.
  Rat   595 TAGQAGPG---RGTTQETQSAPVSS--------SEASFSGSQHY--LQTFPGLPGGGPLTGNQKT 646

  Fly   711 DGGHQNPADVKRRYPSGLIG 730
            ..|....|:...:..:.|:|
  Rat   647 LQGQPKGAEAASKNQTSLLG 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	NURR_Syncrip-like	68..150	CDD:410953
		hnRNP-R-Q	153..>563	CDD:273732	97/472 (21%)
Raver2	XP_038966220.1	RRM_SF	<207..240	CDD:473069	12/33 (36%)
		RRM2_RAVER2	244..320	CDD:410067	22/83 (27%)
		RRM3_RAVER2	330..426	CDD:410069	20/97 (21%)