Protein Alignment Syp and syncrip

DIOPT Version :10

• Sequence 1: NP_001262777.1
• Gene: Syp / 42460
• FlyBaseID: FBgn0038826
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_999861.1
• Gene: syncrip / 326663
• ZFINID: ZDB-GENE-030131-4862
• Length: 630
• Species: Danio rerio
• Alignment Length: 728
• Identity: 326/728 - (44%)
• Similarity: 411/728 - (56%)
• Gaps: 132/728 - (18%)

  Fly    58 ADDRGDGERTED-------------YPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALK 109
            |.:..:|..|||             :..|||.||.:|||.||||||..|.:||::|||||::|||
Zfish     2 ATEHINGNGTEDAMDTAAAVTHSDHFNTLLEAGLPQKVAEKLDEIYLAGLVAHSDLDERAIEALK 66

  Fly   110 EFPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKIL 174
            ||..:|||.||.||.||:|.||.||||:||||||||||:.:   ||.....:.|||||.|||.:|
Zfish    67 EFNEEGALQVLIQFKESDLSHVQNKSAFLCGVMKTYRQREK---QGTKVVESTKGPDEAKIKILL 128

  Fly   175 ERTGYTLDVTTGQRKYGGPPPH--WEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRL 237
            |||||||||||||||||||||.  :.|..|..|.|:|.||||:|::||||:|.||..|.||||||
Zfish   129 ERTGYTLDVTTGQRKYGGPPPESVYTGAQPTVGTEIFVGKIPRDLFEDELVPQFEKAGPIWDLRL 193

  Fly   238 MMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDE 302
            ||||::|.||||||:||..:|||..||:..|:.|||.||.|||.||..|:|||||:|||::.:::
Zfish   194 MMDPLSGLNRGYAFLTFCTKEAAQEAVKLCNNHEIRPGKHIGVCISVANNRLFVGSIPKSKTKEQ 258

  Fly   303 LIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWA 367
            ::|||||...||.:||:|..||||||||||||||||.||.|:.|:|||.:|::||||..:.|:||
Zfish   259 IVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNLVTVEWA 323

  Fly   368 DPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAM 432
            ||.|:||.:.|:|||||:||||...|:|:.|::.|.|:|.:|||||:|||||:||.|||.||:|:
Zfish   324 DPIEDPDPEVMAKVKVLFVRNLANSVTEEILEKAFGQFGNLERVKKLKDYAFVHFNDRDGAVKAL 388

  Fly   433 RGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGFETLSPYRNLSPTHP 497
            ..:||||:...:||:..||||..|:|:.:..|...:..|              ...|....|..
Zfish   389 TEMNGKELEGEHIEIVFAKPPDQKRKERKAQRQAAKTQM--------------YDDYYYYGPPQ- 438

  Fly   498 SIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQ--GGSFGNNVSYYDDMYRWIDGDYNYY 560
                   |.|.||...|......|.|..|::|:.||..  |..:.|....|||.|      :.|.
Zfish   439 -------MPPPARGRGRGASRGGYSYPPDYYGYEDYYDYYGYDYHNYRGGYDDPY------FGYD 490

  Fly   561 DYPNGGGGGSGGGGGSVSGGTVLPLSAGGSQNSPMASGQRSARGSASGPSASPSLMGVGRGHGIT 625
            |:.....|  .||.||..|||                              ||:     ||.|.:
Zfish   491 DFQAPARG--RGGRGSARGGT------------------------------SPA-----RGRGAS 518

  Fly   626 VPRGRVVGQRGSISRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPAATGGFRGVLPTRPSA 690
            .||||.             ..||..||.|..|      |.||..|       |...|||   |..
Zfish   519 APRGRA-------------GFPQRGGAGAGPG------ASRGLRG-------GARGGVL---PRG 554

  Fly   691 RGTQHVKPLQNLPVVGKRKFDGGHQNPADVKRRYPSGLIGNGGSWGSLPLPQQPL------GTNG 749
            ||.:..:..:...|.||||.||  .|..|.|||...     ..:|||.|:.||||      |..|
Zfish   555 RGVRGARGGRGGNVGGKRKADG--YNQPDSKRRQTI-----NQNWGSQPIAQQPLQGGDHSGNYG 612

  Fly   750 -----EQWYMDTF 757
                 :::|.|:|
Zfish   613 YKSDNQEFYQDSF 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	NURR_Syncrip-like	68..150	CDD:410953	55/94 (59%)
		hnRNP-R-Q	153..>563	CDD:273732	209/413 (51%)
syncrip	NP_999861.1	NURR_hnRNPQ	23..107	CDD:410954	53/83 (64%)
		hnRNP-R-Q	103..622	CDD:273732	267/622 (43%)