DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syp and LOC100498620

DIOPT Version :9

Sequence 1:	NP_001262777.1	Gene:	Syp / 42460	FlyBaseID:	FBgn0038826	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	XP_017949185.2	Gene:	LOC100498620 / 100498620	-ID:	-	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	501	Identity:	198/501 - (39%)
Similarity:	272/501 - (54%)	Gaps:	93/501 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 ILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRL 237
            ::::||||:....||||:|||||.|||..|..|||||.||||:|||||||:||||..|.|::.||
Frog    28 LIDKTGYTMVQVNGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPLFERAGKIYEFRL 92

  Fly   238 MMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDE 302
            ||: .:|.|||||||.:||:|.|:.|:|.||::|||.||.|||..|.:|.|||:|:||:.:.:::
Frog    93 MME-FSGENRGYAFVMYTNKEEALLAIRMLNNYEIRQGKFIGVCASLDNCRLFIGSIPQEKRKED 156

  Fly   303 LIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWA 367
            ::||..|...|:.:||:..|..||.|||||.|:.||||:||::|:|:|..|..::||..|.||||
Frog   157 ILEEMKKVTEGVMDVIVCPSATDKTKNRGFAFVTYESHRAAAMARRKLIPGTFQLWGRTIKVDWA 221

  Fly   368 DPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQY--GKVERVKKIKDYAFIHFEDRDSAVE 430
            ||::|.||:||.||||||||||....:|:.:|.:|.:|  |.|||||||:||||:||..||.|:.
Frog   222 DPEKEVDEETMQKVKVLYVRNLMMSTTEETIKAEFNRYKPGVVERVKKIRDYAFVHFFRRDYAIA 286

  Fly   431 AMRGLNGKEIGASNIEVSLAKPPSDK-----------KKKEEIL-----RARERRMMQMMQARPG 479
            ||..:||:.|..:.|||:||||.:.:           ....|.|     :...::::.|....|.
Frog   287 AMSEMNGRLIDGARIEVTLAKPVNKEAAWRQNGNGHMNPNSECLLNFANKEGSQKVLDMCSNVPA 351

  Fly   480 IVGFETLSPYRNLSP--------THPSI--MSLTPMR---------PGARMPLRTPIPREYDYFY 525
            .        |...||        |:|.|  ..||||.         ..|.|.|      ||..:.
Frog   352 Y--------YNQNSPTFLEAERCTYPCIPGTKLTPMNLYSLKINHFHSAVMHL------EYYCYK 402

  Fly   526 DFFGFSDY------RQGGSF------------GNNVSYY--DDMYRWIDG-------------DY 557
            :.:.|.:|      .|.|..            ||..||:  |.:...::.             ||
Frog   403 NNWSFPEYYLYATTGQDGKMLLAYKVIVPAIAGNTNSYFMPDKLCSIVEDAKELAAQFTLMHLDY 467

  Fly   558 NYYDYPNGG------GGGSGGGGGSVSGGTVLPLSAGGSQNSPMAS 597
            :|  :|..|      ...:..|...|...|..|.|.....:||..|
Frog   468 SY--HPTSGKNISLPSTAAASGSSGVLPYTPKPYSYSSYPSSPNVS 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	RRM1_hnRNPR_like	205..283	CDD:240695	50/77 (65%)
		RRM2_hnRNPR_like	286..367	CDD:240696	37/80 (46%)
		RRM3_hnRNPR_like	381..452	CDD:240697	40/72 (56%)
LOC100498620	XP_017949185.2	hnRNP-R-Q	20..488	CDD:273732	190/476 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384330at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010