Protein Alignment Syp and syncrip

DIOPT Version :10

• Sequence 1: NP_001262777.1
• Gene: Syp / 42460
• FlyBaseID: FBgn0038826
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_002933974.2
• Gene: syncrip / 100144726
• XenbaseID: XB-GENE-920046
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 743
• Identity: 324/743 - (43%)
• Similarity: 409/743 - (55%)
• Gaps: 163/743 - (21%)

  Fly    46 GNGELLDDINQKADDRGDGERTEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKE 110
            |||     ..:..|......::|....||:.||.:|||.||||||.:|.:.|::|||||::||||
 Frog     8 GNG-----TEEPMDTYAAVAQSEHMQTLLDAGLPQKVAEKLDEIYISGLVTHSDLDERAIEALKE 67

  Fly   111 FPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKILE 175
            |..:|||.||.||.:|:|.||.||||:||||||||||:.:   ||.....:.|||||.|||.:||
 Frog    68 FNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREK---QGTKVADSSKGPDESKIKALLE 129

  Fly   176 RTGYTLDVTTGQRKYGGPPPHW--EGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLM 238
            ||||||||||||||||||||.:  .|..|..|.|:|.||||:|::||||:||||..|.|||||||
 Frog   130 RTGYTLDVTTGQRKYGGPPPDFVHTGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGSIWDLRLM 194

  Fly   239 MDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDEL 303
            |||:||.|||||||||..:|||..||:..|:.|||.||.|||.||..|:|||||:|||::.::::
 Frog   195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRPGKHIGVCISVANNRLFVGSIPKSKTKEQI 259

  Fly   304 IEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWAD 368
            :|||||...||.:||:|..||||||||||||||||.||.|:.|:|||.:|::||||..:.|:|||
 Frog   260 VEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWAD 324

  Fly   369 PQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAMR 433
            |.|:||.:.|:|||||:||||...|:|:.|::.|.|:||:|||||:||||||||::|..||:||.
 Frog   325 PIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFGQFGKLERVKKLKDYAFIHFDERVGAVKAME 389

  Fly   434 GLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMM---------------QMMQARPGIVGF 483
            .:||||:...|||:..||||..|:|:.:..|...:..|               ...:.|.|..|:
 Frog   390 EMNGKELEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDEYYYYGGPHMPPPSRGRGRGGRGGY 454

  Fly   484 ETLSPYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFS--DYRQGGSFGNNVSYY 546
            ...|.|..                             ||.:||::|:.  :||.|         |
 Frog   455 GYPSDYYG-----------------------------YDDYYDYYGYDYHNYRGG---------Y 481

  Fly   547 DDMYRWIDGDYNYYDYPNGGGGGSGGGGGSVSGGTVLPLSAGGSQNSPMASGQRSARGSASGPSA 611
            ||.:      |.|.|:..|..|..|                            |.|||      |
 Frog   482 DDPF------YGYEDFQVGARGRGG----------------------------RGARG------A 506

  Fly   612 SPSLMGVGRGHGITVPRGRV-VGQRGSISRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPA 675
            :||     ||.|...||||. ..|||.           ...|..|.|....|..|||...:||..
 Frog   507 APS-----RGRGAVPPRGRAGYSQRGG-----------PGSARGARGARGGAQQQRGRGVRGARG 555

  Fly   676 ATGGFRGVLPTRPSARGTQHVKPLQNLPVVGKRKFDGGHQNPADVKRRYPSGLIGNGGSWGSLPL 740
            ..||..|                       ||||.||  .|..|.|||..     |..:|||.|:
 Frog   556 GRGGNVG-----------------------GKRKADG--YNQPDSKRRQT-----NNQNWGSQPI 590

  Fly   741 PQQPL------GTNG-----EQWYMDTF 757
            .||||      |..|     :::|.|:|
 Frog   591 AQQPLQGGDHSGNYGYKSENQEFYQDSF 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syp	NP_001262777.1	NURR_Syncrip-like	68..150	CDD:410953	51/81 (63%)
		hnRNP-R-Q	153..>563	CDD:273732	212/428 (50%)
syncrip	XP_002933974.2	NURR_hnRNPQ	23..107	CDD:410954	51/83 (61%)
		hnRNP-R-Q	103..615	CDD:273732	268/638 (42%)