DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T1 and psmb7

DIOPT Version :9

Sequence 1:	NP_650910.1	Gene:	Prosalpha4T1 / 42457	FlyBaseID:	FBgn0265606	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_021324576.1	Gene:	psmb7 / 64278	ZFINID:	ZDB-GENE-001208-4	Length:	286	Species:	Danio rerio

Alignment Length:	206	Identity:	45/206 - (21%)
Similarity:	81/206 - (39%)	Gaps:	9/206 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DGHLLQVEYAQEAVRK-GSTAVGVRGANCVVLGVEKSSVSEM-QEDRTVRKISMLDRHVALAFAG 77
            :..:.::.::..|.|| |:|..|:...:.||||.:..:...| ..|:...||..:..::....||
Zfish    26 EADITKLGFSSPAARKTGTTICGIVYKDGVVLGADTRATEGMIVADKNCSKIHYISPNIYCCGAG 90

  Fly    78 LTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADG 142
            ..||..:.........:.|.|:......:....|.|.|:..:|     :...|.:.::||:|..|
Zfish    91 TAADTEMTTQIISSNLELHSLSTGRLPRVATANRMLKQMLFRY-----QGYIGAALVLGGVDCTG 150

  Fly   143 SARLFHTEPSGIFHEYKATATGRWANTVREFFEKAY-SDHEVTTKCDAIKLAMRALLEVTQMSQM 206
             ..|:...|.|...:......|..:......||..| .|.|.......::.|:.|.:.....|..
Zfish   151 -PHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDRYRPDMEEEDAKSLVRDAIAAGIFNDLGSGS 214

  Fly   207 RLEVAVLENGK 217
            .::|.|:..||
Zfish   215 NIDVCVITKGK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	PRK03996	5..239	CDD:235192	45/206 (22%)
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	42/200 (21%)
psmb7	XP_021324576.1	proteasome_beta_type_7	44..232	CDD:239732	41/188 (22%)
psmb7	XP_021324576.1	Pr_beta_C	237..280	CDD:315191
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900