DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T1 and PSMB10

DIOPT Version :9

Sequence 1:	NP_650910.1	Gene:	Prosalpha4T1 / 42457	FlyBaseID:	FBgn0265606	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_002792.1	Gene:	PSMB10 / 5699	HGNCID:	9538	Length:	273	Species:	Homo sapiens

Alignment Length:	147	Identity:	36/147 - (24%)
Similarity:	69/147 - (46%)	Gaps:	10/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSE-MQEDRTVRKISMLDRHVALAFAGLTADA 82
            |:|.:|:   :.|:|..|:...:.|:||.:..:.:: :..|::..||..:...:....||:.|||
Human    30 LKVPHAR---KTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADA 91

  Fly    83 RILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADGSARLF 147
            .:.......:.:.|.|:...:..:..:||.|.|...:|     :...|.|.::||:|..| .:|:
Human    92 EMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRY-----QGHVGASLIVGGVDLTG-PQLY 150

  Fly   148 HTEPSGIFHEYKATATG 164
            ...|.|.:.....||.|
Human   151 GVHPHGSYSRLPFTALG 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	PRK03996	5..239	CDD:235192	36/147 (24%)
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	36/147 (24%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	32/134 (24%)
PSMB10	NP_002792.1	Pr_beta_C	232..267	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900