Protein Alignment Prosalpha4T1 and PSMA1

DIOPT Version :10

• Sequence 1: NP_650910.1
• Gene: Prosalpha4T1 / 42457
• FlyBaseID: FBgn0265606
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_683877.1
• Gene: PSMA1 / 5682
• HGNCID: 9530
• Length: 269
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 70/245 - (28%)
• Similarity: 124/245 - (50%)
• Gaps: 7/245 - (2%)

  Fly     3 SRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKISML 67
            ::|...:|::||.|.:.|:|||.|||::||..||::.....||...|.:.||:...:  :||..:
Human    10 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKILHV 72

  Fly    68 DRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGIS 132
            |.|:.::.||||||||:|.|..:.||...|..|:..:.:..:...:....|..||..||||:|:.
Human    73 DNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVG 137

  Fly   133 CLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVTTKCDAIKLAMRAL 197
            .||.|.| |....:|.|.||..:.:.:|.:.|..:.:.|.:.|:..|:.......:.:|..:|||
Human   138 LLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRAL 201

  Fly   198 LEVTQMSQ----MRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAK 243
            .|.....|    ..:.:.::.......:.|...:|..::.::...:.:|:
Human   202 RETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQRKAQ 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	67/211 (32%)
PSMA1	NP_683877.1	proteasome_alpha_type_1	12..222	CDD:239718	67/212 (32%)