DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha4T1 and PSMA1

DIOPT Version :9

Sequence 1:NP_650910.1 Gene:Prosalpha4T1 / 42457 FlyBaseID:FBgn0265606 Length:249 Species:Drosophila melanogaster
Sequence 2:NP_683877.1 Gene:PSMA1 / 5682 HGNCID:9530 Length:269 Species:Homo sapiens


Alignment Length:245 Identity:70/245 - (28%)
Similarity:124/245 - (50%) Gaps:7/245 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 SRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKISML 67
            ::|...:|::||.|.:.|:|||.|||::||..||::.....||...|.:.||:...:  :||..:
Human    10 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKILHV 72

  Fly    68 DRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGIS 132
            |.|:.::.||||||||:|.|..:.||...|..|:..:.:..:...:....|..||..||||:|:.
Human    73 DNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVG 137

  Fly   133 CLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVTTKCDAIKLAMRAL 197
            .||.|.| |....:|.|.||..:.:.:|.:.|..:.:.|.:.|:..|:.......:.:|..:|||
Human   138 LLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRAL 201

  Fly   198 LEVTQMSQ----MRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAK 243
            .|.....|    ..:.:.::.......:.|...:|..::.::...:.:|:
Human   202 RETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQRKAQ 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha4T1NP_650910.1 PRK03996 5..239 CDD:235192 69/237 (29%)
proteasome_alpha_type_7 5..213 CDD:239724 67/211 (32%)
PSMA1NP_683877.1 proteasome_alpha_type_1 12..222 CDD:239718 67/212 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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