DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T1 and Prosbeta2

DIOPT Version :9

Sequence 1:	NP_650910.1	Gene:	Prosalpha4T1 / 42457	FlyBaseID:	FBgn0265606	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	31/151 - (20%)
Similarity:	64/151 - (42%)	Gaps:	7/151 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RKGSTAVGVRGANCVVLGVE-KSSVSEMQEDRTVRKISMLDRHVALAFAGLTADARILINRGQVE 92
            :.|:|.||:...:.|:||.: :::...:..|:...||..|.:::....||..||..:..:....:
  Fly    37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQ 101

  Fly    93 CQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADGSARLFHTEPSGIFHE 157
            .:.|||..:.:|.:......|.|:..:|     :.....:.::||:|..| ..::...|.|...:
  Fly   102 LELHRLQTDREVRVVAANTMLKQMLFRY-----QGHISAALVLGGVDKTG-PHIYSIHPHGSSDK 160

  Fly   158 YKATATGRWANTVREFFEKAY 178
            ......|..:......||..:
  Fly   161 LPYATMGSGSLAAMTVFESRW 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	PRK03996	5..239	CDD:235192	31/151 (21%)
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	31/151 (21%)
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	29/146 (20%)
		proteasome_beta_type_7	42..228	CDD:239732	29/146 (20%)
		Pr_beta_C	232..264	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930