DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T1 and psmb8a

DIOPT Version :9

Sequence 1:	NP_650910.1	Gene:	Prosalpha4T1 / 42457	FlyBaseID:	FBgn0265606	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_571467.3	Gene:	psmb8a / 30666	ZFINID:	ZDB-GENE-990415-141	Length:	271	Species:	Danio rerio

Alignment Length:	166	Identity:	35/166 - (21%)
Similarity:	71/166 - (42%)	Gaps:	32/166 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GSTAVGVRGANCVVLGVE-KSSVSEMQEDRTVRKISMLDRHVALAFAGLTADA----RILINRGQ 90
            |:|.:..:..:.|::.|: ::|..:....:...|:..::.::....:|..||.    |:|..
Zfish    67 GTTTLAFKFRHGVIVAVDSRASAGKYIASKEANKVIEINPYLLGTMSGSAADCQYWERLLAK--- 128

  Fly    91 VECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGIS--CLIGGIDADG----------- 142
             ||:.::|..:.::::...::.|:.:...|      |..|:|  .:|.|.|..|
Zfish   129 -ECRLYKLRNKQRISVSAASKLLSNMMLGY------RGMGLSMGSMICGWDKQGPGLYYVDDNGT 186

  Fly   143 --SARLFHTEPSGIFHEYKATATG-RWANTVREFFE 175
              |.|:|.| ..|..:.|....:| |...||.|.:|
Zfish   187 RLSGRMFST-GCGNSYAYGVVDSGYREDMTVEEAYE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	PRK03996	5..239	CDD:235192	35/166 (21%)
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	35/166 (21%)
psmb8a	NP_571467.3	PTZ00488	37..266	CDD:185666	35/166 (21%)
psmb8a	NP_571467.3	proteasome_beta_type_5	68..255	CDD:239730	34/165 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900