DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T1 and Psmb10

DIOPT Version :9

Sequence 1:	NP_650910.1	Gene:	Prosalpha4T1 / 42457	FlyBaseID:	FBgn0265606	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001020808.1	Gene:	Psmb10 / 291983	RGDID:	1307428	Length:	273	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	42/186 - (22%)
Similarity:	74/186 - (39%)	Gaps:	31/186 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 AVRKGSTAVGVRGANCVVLGVEKSSVSE-MQEDRTVRKISMLDRHVALAFAGLTADARILINRGQ 90
            |.:.|:|..|:...:.|:||.:..:.:: :..|::..||..:...:....||:.||..:......
  Rat    35 ARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 99

  Fly    91 VECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADGSARLFHTEPSGIF 155
            .:.:.|.|:...:..:..:||.|.|...:|     :...|.|.::||:|.:| .:|:...|.|.:
  Rat   100 SKMELHALSTGREPRVATVTRILRQTLFRY-----QGHVGASLIVGGVDLNG-PQLYSVHPHGSY 158

  Fly   156 HEYKATATGRWANTVREFFEKAYSDHEVTTKCDAIKLAMRALLEVTQMSQMRLEVA 211
            .....||.|...:                        |..||||......|.||.|
  Rat   159 SRLPFTALGSGQD------------------------AAVALLEDRFQPNMTLEAA 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	PRK03996	5..239	CDD:235192	42/186 (23%)
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	42/186 (23%)
Psmb10	NP_001020808.1	proteasome_beta_type_7	40..226	CDD:239732	40/181 (22%)
Psmb10	NP_001020808.1	Pr_beta_C	233..267	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900