Protein Alignment Prosalpha4T1 and PSMA8

DIOPT Version :10

• Sequence 1: NP_650910.1
• Gene: Prosalpha4T1 / 42457
• FlyBaseID: FBgn0265606
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_653263.2
• Gene: PSMA8 / 143471
• HGNCID: 22985
• Length: 256
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 148/255 - (58%)
• Similarity: 192/255 - (75%)
• Gaps: 7/255 - (2%)

  Fly     1 MSSRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKIS 65
            |:|||.||:|:|||||||.|||||||||:|||||||:||.|.|||||||.||:::|::||||||.
Human     1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKIC 65

  Fly    66 MLDRHVALAFA------GLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCN 124
            .||.||.:|||      |||||||::|||.:||||||:|..|:.||:|||||::|.|||||||.|
Human    66 ALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 130

  Fly   125 GRRPFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVTTKCDA 189
            ||||||||.||.|.|.||.:||:.|:|||.:|.:||.|.||.|.|||||.||.|::..:.:..:|
Human   131 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEA 195

  Fly   190 IKLAMRALLEVTQMSQMRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAKAHKMKR 249
            ||||::|||||.|.....:|:|::...:|:||..:..:...|..::.||| :|:..|.|:
Human   196 IKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKE-EAEKKKSKK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T1	NP_650910.1	proteasome_alpha_type_7	5..213	CDD:239724	135/213 (63%)
PSMA8	NP_653263.2	proteasome_alpha_type_7	5..219	CDD:239724	135/213 (63%)