Protein Alignment Cdk2 and CDK1

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001307847.1
• Gene: CDK1 / 983
• HGNCID: 1722
• Length: 297
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 169/296 - (57%)
• Similarity: 215/296 - (72%)
• Gaps: 12/296 - (4%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::::.:.|||||||||:|||.|..:|||.||:||||||.|.|||||||||||||||.|:|||:|.
Human     1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVS 65

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132
            |.||::..:.||:|||:|:|||||.:|.  ........|:|||::|||..:.|||:.|:||||||
Human    66 LQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLK 130

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            |||||:|..|.||||||||||||.:|:|.|||||||||||:||:|||:..|||.|||||:|.||:
Human   131 PQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAH- 261
            |:..::.||.||||||||:||||.|.||:...||.|..|.|:|..||:|:    |..:..|..:
Human   196 ELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWK----PGSLASHVKNL 256

  Fly   262 -----ELIMSMLCYDPNLRISAKDALQHAYFRNVQH 292
                 :|:..||.|||..|||.|.||.|.||.::.:
Human   257 DENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	169/296 (57%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	167/286 (58%)
CDK1	NP_001307847.1	STKc_CDK1_euk	3..287	CDD:270845	167/287 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750