Protein Alignment Cdk2 and CDK13

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_016868239.1
• Gene: CDK13 / 8621
• HGNCID: 1733
• Length: 1542
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 124/336 - (36%)
• Similarity: 179/336 - (53%)
• Gaps: 54/336 - (16%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            :|.|.....|||||||.|||||...||:.|||||:||:.|.||.|.||||||.:|:.|.|.:::.
Human   702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIIN 766

  Fly    70 LFDVVISGNN----------LYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTN 124
            :.::|....:          .|::|||::.||..|::.....|....|||:|.|:::.:.:||..
Human   767 MKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKK 831

  Fly   125 RILHRDLKPQNLLVDTAGKIKLADFGLAR-------------------------------AFNVP 158
            ..||||:|..|:|::..|:||||||||||                               :|...
Human   832 NFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESAWLMLIWEKVIFIWRILLMQMSAGSFGDS 896

  Fly   159 MRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLS 223
            .|.||::|:|||||.||:|||.:.|:..:|:||.|||..|:..::.:|..:.|:.||..|.|...
Human   897 SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICG 961

  Fly   224 TPDETNWPGVTQLPDFKTKFP--------RWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKD 280
            :|....||.|.:||.|.|..|        |.|...:|.     .|.:|...||..||:.|.:|:.
Human   962 SPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPA-----AALDLFDYMLALDPSKRCTAEQ 1021

  Fly   281 ALQHAYFRNVQ 291
            |||..:.|:|:
Human  1022 ALQCEFLRDVE 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	121/327 (37%)
CDK13	XP_016868239.1	STKc_CDK12	697..1028	CDD:270847	122/330 (37%)