Protein Alignment Cdk2 and PHO85

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_015294.1
• Gene: PHO85 / 856076
• SGDID: S000005952
• Length: 305
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 139/297 - (46%)
• Similarity: 201/297 - (67%)
• Gaps: 13/297 - (4%)

  Fly     8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFD 72
            |::.||:|.|||..|||..:.:||..||||:::|:.| ||.||||||||||:|.|||.|:|:|:|
Yeast     7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHENIVRLYD 70

  Fly    73 VVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQ-----LIKSYMHQILDAVGFCHTNRILHRDLK 132
            |:.:.|.|.::||:::.||||.||.:....||:     |:|.:..|:|..:.|||.|:|||||||
Yeast    71 VIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLK 135

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            |||||::..|::||.||||||||.:|:..::.||||||||||::|:|::.|||.:||||.|||.:
Yeast   136 PQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILA 200

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHE 262
            |||..:.||||.::.:||..||..:.||:|:.||.||:||.:.....:....::.|.:..|....
Yeast   201 EMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEP 265

  Fly   263 L-------IMSMLCYDPNLRISAKDALQHAYFRNVQH 292
            |       :..:|..:|::|:|||.||.|.:|....|
Yeast   266 LDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYH 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	137/290 (47%)
PHO85	NP_015294.1	Protein Kinases, catalytic domain	6..297	CDD:473864	137/290 (47%)