Protein Alignment Cdk2 and CKA1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_012229.1
• Gene: CKA1 / 854776
• SGDID: S000001297
• Length: 372
• Species: Saccharomyces cerevisiae
• Alignment Length: 351
• Identity: 97/351 - (27%)
• Similarity: 170/351 - (48%)
• Gaps: 74/351 - (21%)

  Fly     3 TILD------NFQRAEKIGEGTYGIVYKARSNSTGQDVALK--------------KIRLEGETEG 47
            |::|      :::...|:|.|.|..|::.....:...:.:|              ||..:...|.
Yeast    29 TVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEK 93

  Fly    48 VPSTAI----------REISLLKNLK----------HPNVVQLFDVV---ISGNNLYMIFEYL-N 88
            ||.|.:          ::..:||.::          |.|::.|||::   || ....::|||: |
Yeast    94 VPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPIS-KTPALVFEYVDN 157

  Fly    89 MDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAG-KIKLADFGLA 152
            :|.:.|..|..|:    .|:.||.::|.|:.:||:..|:|||:||.|:::|... |::|.|:|||
Yeast   158 VDFRILYPKLTDL----EIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLA 218

  Fly   153 RAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRS-LFPGDSEIDQLY 216
            ..::|.|. |...|.:.:::.||:|:..:.|...:|:||.|.:.:.||.:|. .|.|.|..|||.
Yeast   219 EFYHVNME-YNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLV 282

  Fly   217 RIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPI-----------TEH-----EAHELIM 265
            :|.:.|.|.|...:     |..::...|| |..:|.|.|           .:|     |..:||.
Yeast   283 KIVKVLGTSDFEKY-----LLKYEITLPR-EFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLID 341

  Fly   266 SMLCYDPNLRISAKDALQHAYFRNVQ 291
            ::|.||...|::||:|:.|.:|..::
Yeast   342 NLLRYDHQERLTAKEAMGHPWFAPIR 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	94/334 (28%)
CKA1	NP_012229.1	STKc_CK2_alpha	21..363	CDD:271034	96/345 (28%)