Protein Alignment Cdk2 and KSS1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_011554.3
• Gene: KSS1 / 852931
• SGDID: S000003272
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 328
• Identity: 108/328 - (32%)
• Similarity: 172/328 - (52%)
• Gaps: 44/328 - (13%)

  Fly     4 ILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL-KHPNV 67
            |...::..:.||||.||.|..|....:|..||:|||:...:...|..| ||||.||:.. :|.|:
Yeast     9 IPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRT-IREIKLLRYFHEHENI 72

  Fly    68 VQLFDVV--IS---GNNLYMIFEYLNMDLKKLMDKKKDVF---TPQLIKSYMHQILDAVGFCHTN 124
            :.:.|.|  :|   .|.:|::.|.:..||:|:::.:...|   :...::.:.:|||.|:...|:.
Yeast    73 ISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSA 137

  Fly   125 RILHRDLKPQNLLVDTAGKIKLADFGLARAF-------NVPMRAYTHEVVTLWYRAPEILLGTKF 182
            :::|||:||.|||:::...:|:.||||||..       ...:...|..|.|.|||||||:|..:.
Yeast   138 QVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQE 202

  Fly   183 YSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTP--DETNWPGVTQLPDFKTKFPR 245
            |:|.:||||.|||.:||:..:.||||.....||:.|...|.||  ::.|.....:..::....|.
Yeast   203 YTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPM 267

  Fly   246 ---------WEGTNM-PQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPV 300
                     |..|:: |..|      :|:..||.::|:.||||.:||:|.|         :|:..
Yeast   268 RPPLPWETVWSKTDLNPDMI------DLLDKMLQFNPDKRISAAEALRHPY---------LAMYH 317

  Fly   301 DPN 303
            ||:
Yeast   318 DPS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	103/306 (34%)
KSS1	NP_011554.3	Protein Kinases, catalytic domain	7..365	CDD:473864	108/328 (33%)