Protein Alignment Cdk2 and KIN28

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_010175.1
• Gene: KIN28 / 851450
• SGDID: S000002266
• Length: 306
• Species: Saccharomyces cerevisiae
• Alignment Length: 308
• Identity: 117/308 - (37%)
• Similarity: 180/308 - (58%)
• Gaps: 24/308 - (7%)

  Fly     8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFD 72
            :.:.:|:|||||.:||....:|||:.:|:|:|:.....:|:..:||||:..|:.::||||::|.|
Yeast     7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELID 71

  Fly    73 VVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLL 137
            :.::.:||.::.|:|..||:.::..|..:|||..||::|...|..|..||.|.||||||||.|||
Yeast    72 IFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLL 136

  Fly   138 VDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMR 202
            ....|:||:||||||||...|....|..|||.||||||:|.|.|.|::.:||||:|.||:|:::|
Yeast   137 FSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLR 201

  Fly   203 RSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHE-------- 259
            ....||.:::||:...||.|.||.:.:||.|       :.|..:....:..|.:..|
Yeast   202 IPYLPGQNDVDQMEVTFRALGTPTDRDWPEV-------SSFMTYNKLQIYPPPSRDELRKRFIAA 259

  Fly   260 ---AHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNA 304
               |.:.:..||..:|..|.:|...|:..||:.:..      |.||::
Yeast   260 SEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPP------PSDPSS 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	112/289 (39%)
KIN28	NP_010175.1	STKc_CDK7	7..302	CDD:270833	117/308 (38%)