Protein Alignment Cdk2 and CAK1

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_116624.1
• Gene: CAK1 / 850515
• SGDID: S000001865
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 337
• Identity: 81/337 - (24%)
• Similarity: 136/337 - (40%)
• Gaps: 90/337 - (26%)

  Fly    35 ALKKIRLEGETEGVPSTAIREISLLKNL--KHPNVVQLFDVVISGNN-LYMIFEYLNMDLKKLM- 95
            |:|.:.|:.:..  |..|..|:|:|..|  |..:::.|.:...:.|| |.::|.:..|:|.:.|
Yeast    29 AIKCLALDFDIP--PHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMNLYEFMQ 91

  Fly    96 -----DKKK-----DVFTPQL--------------------IKSYMHQILDAVGFCHTNRILHRD 130
                 |::|     |:..|.:                    ..|:..|:::.:.|.|.|:|:|||
Yeast    92 MHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRD 156

  Fly   131 LKPQNLLV-----DTAGKIKLADFGL-------ARAFNVPMRAYTHEVVTLWYRAPEILLGTKFY 183
            :||||:::     ..:.|:.:.|||:       ::....||.:...::.|..|:|||:|.|.|.|
Yeast   157 IKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCY 221

  Fly   184 STGVDIWSLGCIFSEMIMRRSLFPG----------------DSEIDQLYRIFRTLSTPDETNWPG 232
            ..|||:|||..|.|:...|.:...|                .|:...:..||..|..|....|..
Yeast   222 DGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEE 286

  Fly   233 VTQL-----------PDFKTKFPRWEGTNMPQPITEHEAHEL---------------IMSMLCYD 271
            |.|.           .|...|:...:..::...|.|.....|               |:.|:.:.
Yeast   287 VAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFS 351

  Fly   272 PNLRISAKDALQ 283
            ||.|.|.:..||
Yeast   352 PNERWSCQRILQ 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	81/337 (24%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	81/337 (24%)
CAK1	NP_116624.1	PKc_like	13..>234	CDD:419665	56/206 (27%)
		PKc_like	<135..363	CDD:419665	57/227 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810