Protein Alignment Cdk2 and CDK11A

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001300825.1
• Gene: CDK11A / 728642
• HGNCID: 1730
• Length: 783
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 136/305 - (44%)
• Similarity: 195/305 - (63%)
• Gaps: 12/305 - (3%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::.||...:|.|||||:||:|:...|.:.||||::::|.|.||.|.|::|||:.:...:|||:|.
Human   423 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 487

  Fly    70 LFDVVISGN--NLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132
            :.::|:..|  .:|::..|:..|||.||:..|..|.|..:|:.|.|:|..|...|.|.|||||||
Human   488 VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLK 552

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            ..|||:..||.:|:.||||||.:..|::|||..|||.||||||:|||.|.|||.||:||:||||.
Human   553 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 617

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDF-KTKFPRWEGTNMPQ---PITEH 258
            |::.::.||||:|||||:.::|:.|.||.|..|||.::||.. |..|......|:.:   .:...
Human   618 ELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD 682

  Fly   259 EAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPN 303
            :..:|:...|.|.|..||||:|.|:|.|||      ...||:||:
Human   683 QGFDLMNKFLTYFPGRRISAEDGLKHEYFR------ETPLPIDPS 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	129/284 (45%)
CDK11A	NP_001300825.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..396
		STKc_CDC2L1	420..711	CDD:173741	129/287 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	721..783		0/1 (0%)