Protein Alignment Cdk2 and cdk5

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_571794.1
• Gene: cdk5 / 65234
• ZFINID: ZDB-GENE-010131-2
• Length: 292
• Species: Danio rerio
• Alignment Length: 287
• Identity: 144/287 - (50%)
• Similarity: 199/287 - (69%)
• Gaps: 5/287 - (1%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            :..:::.|||||||||.|:||::..|.:.||||::||:.:.|||||:|:|||.|||.|||.|:|:
Zfish     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.||:.|...|.::|||.:.||||..|.......|:::||:|:|:|..:.|||:..:||||||||
Zfish    66 LHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQ 130

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||::..|::|||||||||||.:|:|.|:.||||||||.|::|.|.|.|||.:|:||.||||:|:
Zfish   131 NLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195

  Fly   200 I-MRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNM---PQPITEHEA 260
            . ..|.||||:...|||.||||.|.||.|..|..:.:|||:| .:|.:..|..   ..|......
Zfish   196 ANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWQTMNKLPDYK-PYPMYPATTSLVNVVPKLSSTG 259

  Fly   261 HELIMSMLCYDPNLRISAKDALQHAYF 287
            .:|:.::|..:|..||||::||||.||
Zfish   260 RDLLQNLLKCNPVQRISAEEALQHPYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	144/287 (50%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	142/282 (50%)
cdk5	NP_571794.1	STKc_CDK5	3..286	CDD:143344	142/283 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850