Protein Alignment Cdk2 and MOK

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_055041.1
• Gene: MOK / 5891
• HGNCID: 9833
• Length: 419
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 106/307 - (34%)
• Similarity: 169/307 - (55%)
• Gaps: 10/307 - (3%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGET-EGVPSTAIREISLLKNLK-HPNV 67
            :.|::...||||||:..|.|.:|...|...|.|:::...|: |.|.:  :|||..|:.|. |||:
Human     1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN--LREIQALRRLNPHPNI 63

  Fly    68 VQLFDVVI--SGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRD 130
            :.|.:||.  ...:|.:|.|.::|::.:|:..::...:.:.|..||:|:..::...|.|.|.|||
Human    64 LMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRD 128

  Fly   131 LKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCI 195
            :||:|:|: ....:||.|||..|:. ...:.||..:.|.||||||.||...||:..:|:||.||:
Human   129 VKPENILI-KQDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCV 191

  Fly   196 FSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPIT--EH 258
            |.|:...:.||||.:|:||:.:|...:.||.:.......|.......||..:|:.:|...|  ..
Human   192 FYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSP 256

  Fly   259 EAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAG 305
            :...|:.:|:.|||:.||:|..||||.||:..:..:..||.....||
Human   257 QCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHRKAG 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	99/284 (35%)
MOK	NP_055041.1	STKc_MOK	4..285	CDD:270825	99/284 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..344		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	390..419