DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cdk2 and cdk21

DIOPT Version :10

Sequence 1:NP_524420.1 Gene:Cdk2 / 42453 FlyBaseID:FBgn0004107 Length:314 Species:Drosophila melanogaster
Sequence 2:XP_073800979.1 Gene:cdk21 / 569515 ZFINID:ZDB-GENE-131121-149 Length:306 Species:Danio rerio


Alignment Length:316 Identity:110/316 - (34%)
Similarity:168/316 - (53%) Gaps:59/316 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 NFQRAEKIGEGTYGIVYKARSNSTGQD-VALKKIRLEGETE-GVPSTAIREISLLKNLK---HPN 66
            :::...:||:|.||.|||||.....|. :|:|::.:..|.| |:|...|||::||:.::   |||
Zfish    10 DYEILAEIGQGAYGKVYKAREKREQQRLIAVKRLNIPEEPESGIPQFMIREVALLRKIEHFNHPN 74

  Fly    67 VVQLFDVVISGNN----LYMIFEYLNMDLKKLMDKKKDV-FTPQLIKSYMHQILDAVGFCHTNRI 126
            :|:|..|.....|    :.::|||::.||...:.:..:. .....||..|.|:|..:.|.|||.:
Zfish    75 IVKLMSVSAGWQNHKFDMTLVFEYIDQDLTTFLSRASEKGLAKDKIKDVMRQLLSGLDFLHTNSV 139

  Fly   127 LHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWS 191
            :||||||.|:||.:.|::|:|||||||.:...: |.|..||||||||||:||.:. |.:.||:||
Zfish   140 IHRDLKPDNVLVSSRGEVKIADFGLARIYTYRI-ALTPCVVTLWYRAPEVLLQSS-YMSSVDMWS 202

  Fly   192 LGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPIT 256
            .||||:|:.:.|.||.|.:||.||.:||..:..|.:.:||                         
Zfish   203 AGCIFAELFLLRPLFRGFTEIQQLQKIFEVIGLPGKEDWP------------------------- 242

  Fly   257 EHEAHELIMSMLCYDPNLRISAKDALQHA------------YFRNVQHVDHVALPV 300
                   :.|.:||.|.| :..|.|.|..            ::.::|.:  .:|||
Zfish   243 -------VESPVCYSPAL-VEKKPATQVLASLTPEENGLLNFWHSIQFI--ASLPV 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk2NP_524420.1 STKc_CDK1_CdkB_like 8..287 CDD:270829 106/300 (35%)
cdk21XP_073800979.1 None

Return to query results.
Submit another query.