DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk2 and Cdk1

DIOPT Version :9

Sequence 1:	NP_001163666.1	Gene:	Cdk2 / 42453	FlyBaseID:	FBgn0004107	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_062169.1	Gene:	Cdk1 / 54237	RGDID:	2319	Length:	297	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	169/296 - (57%)
Similarity:	216/296 - (72%)	Gaps:	12/296 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::::.:.|||||||||:|||.|..:|||.||:||||||.|.|||||||||||||||.|:|||:|.
  Rat     1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVS 65

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132
            |.||::..:.||:|||:|:|||||.:|.  ........|:|||::|||..:.|||:.|:||||||
  Rat    66 LQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLK 130

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            |||||:|..|.||||||||||||.:|:|.|||||||||||:||:|||:..|||.|||||:|.||:
  Rat   131 PQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAH- 261
            |:..::.||.||||||||:||||.|.||:...||.|..|.|:|..||:|:    |..:..|..:
  Rat   196 ELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWK----PGSLASHVKNL 256

  Fly   262 -----ELIMSMLCYDPNLRISAKDALQHAYFRNVQH 292
                 :|:..||.|||..|||.|.||:|.||.::.:
  Rat   257 DENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDN 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	169/296 (57%)
Cdk2	NP_001163666.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	167/286 (58%)
Cdk1	NP_062169.1	STKc_CDK1_euk	3..287	CDD:270845	167/287 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720