Protein Alignment Cdk2 and CDK18

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_016856912.1
• Gene: CDK18 / 5129
• HGNCID: 8751
• Length: 572
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 143/293 - (48%)
• Similarity: 202/293 - (68%)
• Gaps: 12/293 - (4%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            |:.:.:.:|:|||||..|:|.||..|...||||:||||.| ||.|.|||||:||||||||.|:|.
Human   239 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVT 302

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.|::.:..:|.::||||:.|||:.:|...::.:...:|.:|.|:|..:.:||..:|||||||||
Human   303 LHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQ 367

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||::..|::||||||||||.:||.:.|::||||||||.|::|||:..|||.:|:|.:|||..||
Human   368 NLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEM 432

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT-KFPRWEGTNMPQPITEH----- 258
            ...|.||||.:..::|:.|||.|.||.|..|||||...:|:| .||.:    :|||:..|
Human   433 ATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCY----LPQPLINHAPRLD 493

  Fly   259 -EAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
             :...|:.|:|.|:...|:||:.||.|:|||::
Human   494 TDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	143/293 (49%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	139/285 (49%)
CDK18	XP_016856912.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820