Protein Alignment Cdk2 and CDK17

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_002586.2
• Gene: CDK17 / 5128
• HGNCID: 8750
• Length: 523
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 148/302 - (49%)
• Similarity: 208/302 - (68%)
• Gaps: 13/302 - (4%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::.:.:.||:|||||..|||.||..|...||||:||||.| ||.|.|||||:||||:|||.|:|.
Human   189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 252

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.|:|.:..:|.::||||:.|||:.||...::.:...:|.:::|||..:.:||..::||||||||
Human   253 LHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQ 317

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||::..|::||||||||||.:||.:.|::||||||||.|::|||:..|||.:|:|.:||||.||
Human   318 NLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEM 382

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT-KFPRWEGTNMPQPITEH----- 258
            ...|.||||.:..|:|:.|||.|.||.:..|||::...:||. .||:::    |||:..|
Human   383 ASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYK----PQPLINHAPRLD 443

  Fly   259 -EAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALP 299
             |..|||...|.|:...|:||::|::|.|||::....| |||
Human   444 SEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIH-ALP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	141/285 (49%)
CDK17	NP_002586.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..123
		STKc_PCTAIRE2	185..493	CDD:143377	148/302 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	501..523