Protein Alignment Cdk2 and CDK16

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_011542222.1
• Gene: CDK16 / 5127
• HGNCID: 8749
• Length: 571
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 135/286 - (47%)
• Similarity: 197/286 - (68%)
• Gaps: 4/286 - (1%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            |:.:.:.:|:|||||..|||.:|..|...||||:||||.| ||.|.|||||:||||:|||.|:|.
Human   236 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 299

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.|::.:..:|.::||||:.|||:.:|...::.....:|.::.|:|..:.:||..::||||||||
Human   300 LHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQ 364

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||::..|::||||||||||.::|.:.|::||||||||.|:||||:..|||.:|:|.:||||.||
Human   365 NLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEM 429

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT-KFPRW--EGTNMPQPITEHEAH 261
            ...|.||||.:..:||:.|||.|.||.|..|||:....:||| .:|::  |......|..:.:..
Human   430 ATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA 494

  Fly   262 ELIMSMLCYDPNLRISAKDALQHAYF 287
            :|:..:|.::...||||:||::|.:|
Human   495 DLLTKLLQFEGRNRISAEDAMKHPFF 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	133/281 (47%)
CDK16	XP_011542222.1	STKc_PCTAIRE1	236..532	CDD:270854	135/286 (47%)