Protein Alignment Cdk2 and Cdkl4

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001419046.1
• Gene: Cdkl4 / 503009
• RGDID: 1583704
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 113/302 - (37%)
• Similarity: 176/302 - (58%)
• Gaps: 27/302 - (8%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEG-VPSTAIREISLLKNLKHPNVV 68
            ::.:::..|||||:||:|:|.|:.|:||.||:||. :|.|.:. |...|:|||.:||.|||||:|
  Rat     1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKF-VESEDDPVVRKIALREIRMLKQLKHPNLV 64

  Fly    69 QLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKP 133
            .|.:|......::::|||.:..|...:::..:..:..:|||.:.|.|.|:.|||.:..:|||:||
  Rat    65 NLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKP 129

  Fly   134 QNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSE 198
            :|:|:...|.||:.|||.||.. :|..|||..|.|.||||||:|:|...|.:.||||::||:|:|
  Rat   130 ENILIAKQGVIKICDFGFARIL-IPGDAYTDYVATRWYRAPELLVGDTKYGSSVDIWAVGCVFAE 193

  Fly   199 MIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPR---WEGTNMPQP---ITE 257
            ::..:.|:||.|::||||.|.|||.          ..:|..::.|..   :.|.::|:|   .|.
  Rat   194 LLTGQPLWPGKSDVDQLYLIIRTLG----------KLIPRHQSIFKSNQFFRGISIPEPEDMETL 248

  Fly   258 HEAHELIMSM--------LCYDPNLRISAKDALQHAYFRNVQ 291
            .|....:..|        |..||:.|::....|...||.:.|
  Rat   249 EEKFSNVQPMALSFMKGCLKMDPDERLTCAQLLDSTYFESFQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	110/293 (38%)
Cdkl4	NP_001419046.1	STKc_CDKL1_4	2..286	CDD:270837	110/295 (37%)